A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology

A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …

A gut-derived metabolite alters brain activity and anxiety behaviour in mice

BD Needham, M Funabashi, MD Adame, Z Wang… - Nature, 2022 - nature.com
Integration of sensory and molecular inputs from the environment shapes animal behaviour.
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …

Bioaccumulation of therapeutic drugs by human gut bacteria

M Klünemann, S Andrejev, S Blasche, A Mateus… - Nature, 2021 - nature.com
Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic map** of the interactions between drugs and bacteria has only started …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Microbiota regulate social behaviour via stress response neurons in the brain

WL Wu, MD Adame, CW Liou, JT Barlow, TT Lai… - Nature, 2021 - nature.com
Social interactions among animals mediate essential behaviours, including mating,
nurturing, and defence,. The gut microbiota contribute to social activity in mice,, but the gut …

Zebrafish as an animal model for biomedical research

TY Choi, TI Choi, YR Lee, SK Choe… - Experimental & Molecular …, 2021 - nature.com
Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …

Gut bacteria and neurotransmitters

LMT Dicks - Microorganisms, 2022 - mdpi.com
Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

[HTML][HTML] The role of short-chain fatty acids from gut microbiota in gut-brain communication

YP Silva, A Bernardi, RL Frozza - Frontiers in endocrinology, 2020 - frontiersin.org
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

Polystyrene nanoplastics toxicity to zebrafish: dysregulation of the brain–intestine–microbiota axis

M Teng, X Zhao, C Wang, C Wang, JC White, W Zhao… - ACS …, 2022 - ACS Publications
In animal species, the brain–gut axis is a complex bidirectional network between the
gastrointestinal (GI) tract and the central nervous system (CNS) consisting of numerous …