Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

Brain metastases from breast cancer (BCBM) constitute the second most common cause of
brain metastasis (BM), and the incidence of these frequently lethal lesions is currently …

Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …

PURPOSE Conventional wisdom has rendered patients with brain metastases ineligible for
clinical trials for fear that poor survival could mask the benefit of otherwise promising …

This study is the first proof of concept that the FLASH effect can be triggered by X-rays. Our
results show that a 10 Gy whole-brain irradiation delivered at ultra-high dose-rate with …

Neuroimaging plays an ever evolving role in the diagnosis, treatment planning, and post-
therapy assessment of brain tumors. This review provides an overview of current magnetic …

Purpose Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may
play a role in memory decline. Intensity-modulated radiotherapy can be used to avoid …

Background We aimed to examine whether stereotactic radiosurgery without whole-brain
radiotherapy (WBRT) as the initial treatment for patients with five to ten brain metastases is …

Purpose To perform an individual patient data (IPD) meta-analysis of randomized controlled
trials evaluating stereotactic radiosurgery (SRS) with or without whole-brain radiation …

Background Metastatic breast cancer (MBC) behaviour differs depending on hormone
receptors (HR) and human epidermal growth factor receptor (HER2) statuses. Methods The …