Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Recently, there has been an exponential growth in the number of publications focusing on
surface-enhanced Raman scattering (SERS), primarily driven by advancements in …

The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …

Although the endoplasmic reticulum (ER) extends throughout axons and axonal ER
dysfunction is implicated in numerous neurological diseases, its role at nerve terminals is …

Astrocytes are abundant glial cells that tile the entire central nervous system and mediate
well-established functions for neurons, blood vessels, and other glia. These ubiquitous cells …

We introduce a family of bright, rhodamine-based calcium indicators with tuneable affinities
and colors. The indicators can be specifically localized to different cellular compartments …

Reversibly photo-switchable proteins are essential for many super-resolution fluorescence
microscopic and optoacoustic imaging methods. However, they have yet to be used as …

Ailment related to pathogenic bacteria and toxins remains a significant threat to the human
body. Specifically, pathogenic bacteria are the main source of epidemic diseases and are …

The interior lumen of acidic organelles (eg, endosomes, secretory granules, lysosomes and
plant vacuoles) is an important platform for modification, transport and degradation of …

Optical Ca 2+ indicators are powerful tools for investigating intracellular Ca 2+ signals in
living cells. Although a variety of Ca 2+ indicators have been developed, deciphering the …