Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

The prevalence and intensity of infections caused by protozoa, nematodes, trematodes,
cestodes, and arthropods is higher in males than females. The primary thesis of this review …

Fig 1. Schematic representation of the systemic inflammatory response (SIRS) to injury,
followed by a period of convalescence mediated by counter-regulatory anti-inflammatory …

The inflammatory response is a highly regulated physiological process that is critically
important for homeostasis. A precise physiological control of inflammation allows a timely …

Glucocorticoids are powerful regulators of immune function. Their role in reducing
inflammation and autoimmune responses is well known, as is their ability to induce …

Recent investigations provided evidence that the sphingomyelin signal transduction
pathway mediates apoptosis for tumor necrosis factor c~(TNF-o 0 in several hematopoietic …

In a number of experimental systems in which lymphocyte depletion was induced by
apoptosis-inducing manipulations, no apoptotic morphology and ladder-type DNA …

The concept of an integrated bidirectionally regulated neuroendocrine-immune adaptive
response to stress has strong experimental support. The quality and intensity of this …

Cytokine storm syndromes (CSS) are severe hyperinflammatory conditions characterized by
excessive immune system activation leading to organ damage and death. Hemophagocytic …

B chronic lymphocytic leukemia (B-CLL) is characterized by the accumulation of slow-
dividing and long-lived monoclonal B cells arrested at the intermediate stage of their …