Reversible phospho-dephosphorylation of proteins is a major mechanism for the control of
cellular functions. By large, Ser and Thr are the most frequently residues phosphorylated in …

CDC14, originally identified as crucial mediator of mitotic exit in budding yeast, belongs to
the family of dual‐specificity phosphatases (DUSPs) that are present in most eukaryotes …

The target of rapamycin complex 1 (TORC1) pathway couples nutrient, energy and
hormonal signals with eukaryotic cell growth and division. In yeast, TORC1 coordinates …

How cells coordinate growth and division is key for size homeostasis. Phosphorylation by
G1-CDK of Whi5/Rb inhibitors of SBF/E2F transcription factors triggers irreversible S-phase …

The yeast Saccharomyces cerevisiae is a powerful model system that is often used to
expand our understanding of cellular processes and biological functions. Although many …

Eukaryotic cell cycle progression through G 1–S is driven by hormonal and growth-related
signals that are transmitted by the target of rapamycin complex 1 (TORC1) pathway. In yeast …

Entry into mitosis requires the coordinated activation of various protein kinases and
phosphatases that together activate sequential signaling pathways allowing entry …

Budding yeast Rho1 guanosine triphosphatase (GTPase) plays an essential role in
polarized cell growth by regulating cell wall glucan synthesis and actin organization. Upon …

The budding yeast Saccharomyces cerevisiae is a powerful model system that is widely
used to investigate many cellular processes. The harvesting of yeast cells is the first step in …

Cell proliferation and cellular quiescence/G0 phase must be regulated in response to intra‐
/extracellular environments, and such regulation is achieved by the orchestration of protein …