Autophagy is a major protein turnover pathway by which cellular components are delivered
into the lysosomes for degradation and recycling. This intracellular process is able to …

Erythropoiesis is a multi‐step process that involves the differentiation of hematopoietic stem
cells into mature red blood cells (RBCs). This process is regulated by several signaling …

ABSTRACT LC3-dependent EV loading and secretion (LDELS) is a secretory autophagy
pathway in which the macroautophagy/autophagy machinery facilitates the packaging of …

Autophagy is an intracellular degradation system that ensures a dynamic recycling of a
variety of building blocks required for self‐renewal, homeostasis, and cell survival under …

In this short review, we presented and discussed studies on the expression of globin genes
in β-thalassemia, focusing on the impact of α-globin gene expression and α-globin modifiers …

Changes to the membrane proteins and rearrangement of the cytoskeleton must occur for a
reticulocyte to mature into a red blood cell (RBC). Different mechanisms of reticulocyte …

Background Intracerebral hemorrhage (ICH) has a high morbidity and mortality. The
peripheral immune system and cross-talk between peripheral blood and brain have been …

Red blood cells, or erythrocytes, make up approximately a quarter of all cells in the human
body with over 2 billion new erythrocytes made each day in a healthy adult human. This …

In the last few years, erythrocytes have emerged as the main determinant of blood rheology.
In mammals, these cells are devoid of nuclei and are, therefore, unable to divide …

Abstract β-thalassemia is a condition characterized by reduced or absent synthesis of β-
globin resulting from genetic mutations, leading to expanded and ineffective erythropoiesis …