Superparamagnetic iron oxide nanoparticulate system: synthesis, targeting, drug delivery and therapy in cancer

S Palanisamy, YM Wang - Dalton transactions, 2019 - pubs.rsc.org
Cancer is a global epidemic and is considered a leading cause of death. Various cancer
treatments such as chemotherapy, surgery, and radiotherapy are available for the cure but …

Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances

K Hola, Z Markova, G Zoppellaro, J Tucek… - Biotechnology advances, 2015 - Elsevier
In this critical review, we outline various covalent and non-covalent approaches for the
functionalization of iron oxide nanoparticles (IONPs). Tuning the surface chemistry and …

Recent progress in biomedical applications of Pluronic (PF127): Pharmaceutical perspectives

MSH Akash, K Rehman - Journal of Controlled Release, 2015 - Elsevier
Most of the administered anti-cancer drugs are hydrophobic in nature and are known to
have poor water solubility, short residence time, rapid clearance from the body and systemic …

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

K Nepali, S Sharma, M Sharma, PMS Bedi… - European journal of …, 2014 - Elsevier
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

In Vivo Biodistribution of Nanoparticles

JPM Almeida, AL Chen, A Foster, R Drezek - Nanomedicine, 2011 - Taylor & Francis
Nanoparticles have potential applications in diagnostics, imaging, gene and drug delivery
and other types of therapy. Iron oxide nanoparticles, gold nanoparticles and quantum dots …

Surface engineering of iron oxide nanoparticles for targeted cancer therapy

FM Kievit, M Zhang - Accounts of chemical research, 2011 - ACS Publications
Nanotechnology provides a flexible platform for the development of effective therapeutic
nanomaterials that can interact specifically with a target in a biological system and provoke a …

Molecular imaging with theranostic nanoparticles

JV Jokerst, SS Gambhir - Accounts of chemical research, 2011 - ACS Publications
Nanoparticles (NPs) offer diagnostic and therapeutic capabilities not available with small
molecules or microscale tools. As the field of molecular imaging has emerged from the …

Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers

FM Kievit, M Zhang - Advanced materials, 2011 - Wiley Online Library
Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …

Enhanced retention and cellular uptake of nanoparticles in tumors by controlling their aggregation behavior

X Liu, Y Chen, H Li, N Huang, Q **, K Ren, J Ji - ACS nano, 2013 - ACS Publications
Effective accumulation of nanoparticles (NPs) in tumors is crucial for NP-assisted cancer
diagnosis and treatment. With the hypothesis that aggregation of NPs stimulated by tumor …

Nano‐biotechnology and challenges of drug delivery system in cancer treatment pathway

E Asadipour, M Asgari, P Mousavi… - Chemistry & …, 2023 - Wiley Online Library
In this review, we discuss Nanotechnology models, which have been developed recently in
cancer treatment. Nanotechnology manipulates matter at the atomic and molecular scale to …