Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Sex steroids and autoimmune rheumatic diseases: state of the art

M Cutolo, RH Straub - Nature Reviews Rheumatology, 2020 - nature.com
In autoimmune rheumatic diseases, oestrogens can stimulate certain immune responses
(including effects on B cells and innate immunity), but can also have dose-related anti …

Systemic immune-inflammation index and bone mineral density in postmenopausal women: a cross-sectional study of the national health and nutrition examination …

Y Tang, B Peng, J Liu, Z Liu, Y **a, B Geng - Frontiers in immunology, 2022 - frontiersin.org
Background This study aimed to investigate the association between the systemic immune-
inflammation index (SII) and bone mineral density (BMD) and to determine the association …

Osteoporosis, osteoarthritis, and subchondral insufficiency fracture: recent insights

S Yokota, H Ishizu, T Miyazaki, D Takahashi, N Iwasaki… - Biomedicines, 2024 - mdpi.com
The increased incidence of osteoarthritis (OA), particularly knee and hip OA, and
osteoporosis (OP), owing to population aging, have escalated the medical expense burden …

A comprehensive review on environmental pollutants and osteoporosis: Insights into molecular pathways

PS Priya, PP Nandhini, J Arockiaraj - Environmental Research, 2023 - Elsevier
A significant problem that has an impact on community wellbeing is environmental pollution.
Environmental pollution due to air, water, or soil pollutants might pose a severe risk to global …

[HTML][HTML] Ideal food pyramid for patients with rheumatoid arthritis: A narrative review

M Rondanelli, F Perdoni, G Peroni, R Caporali… - Clinical Nutrition, 2021 - Elsevier
Emerging literature suggests that diet plays an important modulatory role in rheumatoid
arthritis (RA) because diet is an environmental factor that affects inflammation, antigen …

Association between exposure to fine particulate matter and osteoporosis: a population-based cohort study

G Adami, G Cattani, M Rossini, O Viapiana… - Osteoporosis …, 2022 - Springer
Long-term environmental air pollution exposure was associated with osteoporosis' risk in a
cohort of women at high risk of fracture. Cortical sites seemed to be more susceptible to the …

[HTML][HTML] Effect of long-term exposure to PM2. 5 on the risk of type 2 diabetes and arthritis in type 2 diabetes patients: Evidence from a national cohort in China

C Liu, G Cao, J Li, S Lian, K Zhao, Y Zhong, J Xu… - Environment …, 2023 - Elsevier
Background It remains unclear whether type 2 diabetes and the complication of arthritis are
causally related to the PM 2.5 pollutant. Therefore, we aimed to investigate the associations …

Bone loss in inflammatory rheumatic musculoskeletal disease patients treated with low‐dose glucocorticoids and prevention by anti‐osteoporosis medications

G Adami, A Fassio, M Rossini, C Benini… - Arthritis & …, 2023 - Wiley Online Library
Objective The negative effects of glucocorticoids on bone depend on dose and treatment
duration. However, it is unclear whether a safe dose exists, especially for patients with …

[HTML][HTML] Lupus Nephritis from Pathogenesis to New Therapies: An Update

A Roveta, EL Parodi, B Brezzi, F Tunesi… - International journal of …, 2024 - mdpi.com
Lupus Nephritis (LN) still represents one of the most severe complications of Systemic
Lupus Erythematosus (SLE) and a major risk factor for morbidity and mortality. However …