There are 3 physiological waves of central hypothalamic-pituitary-gonadal (HPG) axis
activity over the lifetime. The first occurs during fetal life, the second—termed “mini-puberty” …

A growing body of evidence exhibits the ubiquitous presence and accumulation of micro-
and nanoplastics (MNPs) in the air, drinking water, food, and even inside the body, which …

The niche has been shown to control stem cell self-renewal in different tissue types and
organisms. Recently, a separate niche has been proposed to control stem cell progeny …

Many laboratory studies demonstrated that the exposure to microplastics causes
testosterone deficiency and spermatogenic impairment in mammals; however, the …

The testis is pivotal for male reproduction, and its progressive functional decline in aging is
associated with infertility. However, the regulatory mechanism underlying primate testicular …

Non-obstructive azoospermia (NOA) is a serious cause of male infertility. The Sertoli cell
responds to androgens and takes on roles supporting spermatogenesis, which may cause …

Background Triptolide (TP) is an important active compound from Tripterygium wilfordii Hook
F (Tw HF), however, it is greatly limited in clinical practice due to its severe toxicity …

The reciprocal crosstalk between testicular Sertoli and Leydig cells plays a vital role in
supporting germ cell development and maintaining testicular characteristics and …

The potential impact of the combination of a high‐fat diet (HFD) and polystyrene
nanoplastics (PS‐NPs) on fertility cannot be ignored, especially when the fertility rate is …

The widespread application of zinc oxide nanoparticles (ZnO NPs) in our daily life has
initiated an enhanced awareness of their biosafety concern. An incredible boom of evidence …