Background Tea trees originated in southwest China 60 million or 70 million years ago.
Written records show that Chinese ancestors had begun drinking tea over 3000 years ago …

Single-molecule technology stands as a powerful tool, enabling the characterization of
intricate structural and dynamic information that would otherwise remain concealed within …

Non-alcoholic fatty liver disease (NAFLD) is regarded as a pandemic that affects about a
quarter of the global population. Recently, host-gut microbiota metabolic interactions have …

Abstract Background Tea (Camellia sinensis) has a rich history and is widely consumed
across many countries, and is categorized into green tea, white tea, oolong tea, yellow tea …

Calorie restriction (CR) and fasting are common approaches to weight reduction, but the
maintenance is difficult after resuming food consumption. Meanwhile, the gut microbiome …

Farnesoid X receptor (FXR) is a ligand-activated transcription factor involved in the control of
bile acid (BA) synthesis and enterohepatic circulation. FXR can influence glucose and lipid …

The low-carbohydrate ketogenic diet (KD) has long been practiced for weight loss, but the
underlying mechanisms remain elusive. Gut microbiota and metabolites have been …

Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

The gut microbiota (GM) is defined as the community of microorganisms (bacteria, archaea,
fungi, viruses) colonizing the gastrointestinal tract. GM regulates various metabolic pathways …