In addition to immediate implications for pregnancy complications, increasing evidence
implicates maternal obesity as a major determinant of offspring health during childhood and …

Context Mounting evidence suggests that the origins of childhood obesity and related
disparities can be found as early as the “first 1,000 days”—the period from conception to age …

Triangulation is the practice of obtaining more reliable answers to research questions
through integrating results from several different approaches, where each approach has …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Background The early life environment experienced by an individual in utero and during the
neonatal period is a major factor in sha** later life disease risk-including susceptibility to …

Maternal lifestyle during pregnancy, as well as early nutrition and the environment infants
are raised in, are considered relevant factors for the prevention of childhood obesity. Several …

Abstract Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic, a
Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …

Abstract The Avon Longitudinal Study of Parents and Children (ALSPAC) is a
transgenerational prospective observational study investigating influences on health and …

Abstract Summary The Avon Longitudinal Study of Children and Parents (ALSPAC) was
established to understand how genetic and environmental characteristics influence health …

Objective To determine the effect of antenatal dietary and lifestyle interventions on health
outcomes in overweight and obese pregnant women. Design Multicentre randomised trial …