Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
CL Sears, JB Kaper - Microbiological reviews, 1996 - Am Soc Microbiol
Bacteria that colonize the intestine, invade intestinal epithelial cells, and/or produce one or
more toxins are important etiologies of diarrheal disease in both industrialized and …
more toxins are important etiologies of diarrheal disease in both industrialized and …
The contribution of cytolethal distending toxin to bacterial pathogenesis
JL Smith, DO Bayles - Critical reviews in microbiology, 2006 - Taylor & Francis
Cytolethal distending toxin (CDT) is a bacterial toxin that initiates a eukaryotic cell cycle
block at the G2 stage prior to mitosis. CDT is produced by a number of bacterial pathogens …
block at the G2 stage prior to mitosis. CDT is produced by a number of bacterial pathogens …
DNase I homologous residues in CdtB are critical for cytolethal distending toxin‐mediated cell cycle arrest
CA Elwell, LA Dreyfus - Molecular microbiology, 2000 - Wiley Online Library
Cytolethal distending toxins (CDTs) block cell division by arresting the eukaryotic cell cycle
at G2/M. Although previously not recognized in standard blast searches, a position‐specific …
at G2/M. Although previously not recognized in standard blast searches, a position‐specific …
The cytolethal distending toxin family
CL Pickett, CA Whitehouse - Trends in microbiology, 1999 - cell.com
Cytolethal distending toxins are produced by a small but diverse group of bacterial
pathogens. This newly discovered toxin family can cause a variety of mammalian cells to …
pathogens. This newly discovered toxin family can cause a variety of mammalian cells to …
Diarrhoeagenic Escherichia coli—an emerging problem?
SC Clarke - Diagnostic microbiology and infectious disease, 2001 - Elsevier
Diarrhea remains one of the main sources of morbidity and morbidity in todays world and a
large proportion is caused by diarrheagenic Escherichia coli. They are a particuar problem …
large proportion is caused by diarrheagenic Escherichia coli. They are a particuar problem …
Cloning and sequencing of the genes encoding Escherichia coli cytolethal distending toxin
DA Scott, JB Kaper - Infection and immunity, 1994 - Am Soc Microbiol
Escherichia coli strains expressing cytolethal distending toxin (CDT) cause elongation of
CHO cells at 24 h, followed by progressive cellular distention and death for up to 120 h …
CHO cells at 24 h, followed by progressive cellular distention and death for up to 120 h …
Gastroenteritis in NF-κB-Deficient Mice Is Produced with Wild-Type Camplyobacter jejuni but Not with C. jejuni Lacking Cytolethal Distending Toxin despite …
JG Fox, AB Rogers, MT Whary, Z Ge… - Infection and …, 2004 - Am Soc Microbiol
Campylobacter jejuni continues to be a leading cause of bacterial enteritis in humans.
However, because there are no readily available animal models to study the pathogenesis …
However, because there are no readily available animal models to study the pathogenesis …
Production of cytolethal distending toxins by pathogenic Escherichia coli strains isolated from human and animal sources: establishment of the existence of a new cdt …
Three types of cytolethal distending toxin (CDT), namely, CDT-I, CDT-II, and CDT-III, have
been described in Escherichia coli. Using primers designed for the detection of sequences …
been described in Escherichia coli. Using primers designed for the detection of sequences …
Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes
CL Pickett, DL Cottle, EC Pesci, G Bikah - Infection and immunity, 1994 - Am Soc Microbiol
A limited number of Escherichia coli isolates which produce an apparently novel toxin,
termed cytolethal distending toxin (CDT), have been reported. The toxic activity produced by …
termed cytolethal distending toxin (CDT), have been reported. The toxic activity produced by …
Identification of a Cytolethal Distending Toxin Gene Locus and Features of a Virulence-Associated Region inActinobacillus actinomycetemcomitans
MPA Mayer, LC Bueno, EJ Hansen… - Infection and …, 1999 - Am Soc Microbiol
ABSTRACT A genetic locus for a cytolethal distending toxin (CDT) was identified in a
polymorphic region of the chromosome of Actinobacillus actinomycetemcomitans, a …
polymorphic region of the chromosome of Actinobacillus actinomycetemcomitans, a …