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What are white matter hyperintensities made of? Relevance to vascular cognitive impairment
JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - ahajournals.org
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …
The importance of comorbidities in ischemic stroke: Impact of hypertension on the cerebral circulation
Comorbidities are a hallmark of stroke that both increase the incidence of stroke and worsen
outcome. Hypertension is prevalent in the stroke population and the most important …
outcome. Hypertension is prevalent in the stroke population and the most important …
Challenging the ischemic core concept in acute ischemic stroke imaging
Endovascular treatment is a highly effective therapy for acute ischemic stroke due to large
vessel occlusion and has recently revolutionized stroke care. Oftentimes, ischemic core …
vessel occlusion and has recently revolutionized stroke care. Oftentimes, ischemic core …
Cerebral collateral circulation in the era of reperfusion therapies for acute ischemic stroke
Clinical outcomes of patients with acute ischemic stroke depend in part on the extent of their
collateral circulation. A good collateral circulation has also been associated with greater …
collateral circulation. A good collateral circulation has also been associated with greater …
WMH and long-term outcomes in ischemic stroke: a systematic review and meta-analysis
Objective To investigate the relationship between baseline white matter hyperintensities
(WMH) in patients with ischemic stroke and long-term risk of dementia, functional …
(WMH) in patients with ischemic stroke and long-term risk of dementia, functional …
Damaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanisms
LR Freeman, V Haley-Zitlin… - Nutritional …, 2014 - Taylor & Francis
The prevalence of obesity is growing and now includes at least one-third of the adult
population in the United States. As obesity and dementia rates reach epidemic proportions …
population in the United States. As obesity and dementia rates reach epidemic proportions …
Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates
JD Schmahmann, EE Smith, FS Eichler… - Annals of the New …, 2008 - Wiley Online Library
Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes,
neuropsychiatric phenomena, and dementia. The cerebral WM contains fiber pathways that …
neuropsychiatric phenomena, and dementia. The cerebral WM contains fiber pathways that …
Stroke outcomes are worse with larger leukoaraiosis volumes
WS Ryu, SH Woo, D Schellingerhout, MU Jang… - Brain, 2017 - academic.oup.com
Leukoaraiosis or white matter hyperintensities are frequently observed on magnetic
resonance imaging of stroke patients. We investigated how white matter hyperintensity …
resonance imaging of stroke patients. We investigated how white matter hyperintensity …
Clinically confirmed stroke with negative diffusion-weighted imaging magnetic resonance imaging: longitudinal study of clinical outcomes, stroke recurrence, and …
SDJ Makin, FN Doubal, MS Dennis, JM Wardlaw - Stroke, 2015 - ahajournals.org
Background and Purpose—We sought to establish whether the presence (versus absence)
of a lesion on magnetic resonance imaging (MRI) with diffusion weighting (DWI-MRI) at …
of a lesion on magnetic resonance imaging (MRI) with diffusion weighting (DWI-MRI) at …
Severity of leukoaraiosis correlates with clinical outcome after ischemic stroke
Background: Leukoaraiosis (LA) is closely associated with aging, a major determinant of
clinical outcome after ischemic stroke. In this study we sought to identify whether LA …
clinical outcome after ischemic stroke. In this study we sought to identify whether LA …