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Lipid abnormalities and inflammation in HIV inflection
Infection with the human immunodeficiency virus (HIV), and subsequent treatment with
antiretroviral therapy (ART), is often associated with perturbations in lipid profiles …
antiretroviral therapy (ART), is often associated with perturbations in lipid profiles …
HIV and cardiovascular disease: the role of inflammation
Mechanistic studies into the drivers of chronic inflammation in PWH are ongoing and may
aid in tailoring effective therapeutic strategies that can reduce ASCVD risk in this population …
aid in tailoring effective therapeutic strategies that can reduce ASCVD risk in this population …
HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults
People with human immunodeficiency virus (HIV) have higher rates of certain comorbidities,
particularly cardiovascular disease and cancer, than people without HIV,,,–. In view of …
particularly cardiovascular disease and cancer, than people without HIV,,,–. In view of …
The role of IL‐1β during human immunodeficiency virus type 1 infection
Abstract Interleukin (IL)‐1β is a key innate cytokine that is essential for immune activation
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
Regulation and functions of the NLRP3 inflammasome in RNA virus infection
Z Yue, X Zhang, Y Gu, Y Liu, LM Lan, Y Liu… - Frontiers in Cellular …, 2024 - frontiersin.org
Virus infection is one of the greatest threats to human life and health. In response to viral
infection, the host's innate immune system triggers an antiviral immune response mostly …
infection, the host's innate immune system triggers an antiviral immune response mostly …
Monocytes as regulators of inflammation and HIV‐related comorbidities during cART
Combined antiretroviral therapy (cART) extends the lifespan and the quality of life for HIV‐
infected persons but does not completely eliminate chronic immune activation and …
infected persons but does not completely eliminate chronic immune activation and …
Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is …
LC Ndhlovu, T Umaki, GM Chew, DC Chow… - Journal of …, 2014 - Springer
HIV-associated neurocognitive disorders (HAND) continues to be prevalent (30–50%)
despite plasma HIV-RNA suppression with combination antiretroviral therapy (cART). There …
despite plasma HIV-RNA suppression with combination antiretroviral therapy (cART). There …
Role of inflammasomes in HIV-1 infection and treatment
Although combined antiretroviral therapy (cART) is effective in inhibiting human
immunodeficiency virus type 1 (HIV-1) replication, it does not eradicate the virus because …
immunodeficiency virus type 1 (HIV-1) replication, it does not eradicate the virus because …
Adipose tissue in HIV infection
JR Koethe - Comprehensive Physiology, 2017 - pmc.ncbi.nlm.nih.gov
HIV infection and antiretroviral therapy (ART) treatment exert diverse effects on adipocytes
and stromal-vascular fraction cells, leading to changes in adipose tissue quantity …
and stromal-vascular fraction cells, leading to changes in adipose tissue quantity …
Downregulation of interferon-β and inhibition of TLR3 expression are associated with fatal outcome of severe fever with thrombocytopenia syndrome
Abstract Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious
disease with high mortality and increasing prevalence in the East Asia. Though the …
disease with high mortality and increasing prevalence in the East Asia. Though the …