Catalytic antibodies made it feasible to develop new catalysts, which had previously been
the subject of research. Scientists have discovered natural antibodies that can hydrolyze …

A robust cell-free platform technology, ribosome display in combination with cloning,
expression, and purification was utilized to develop single chain Fragment variable (scFv) …

SARS-CoV-2 is highly homologous to SARS-CoV. To date, the main protease (Mpro) of
SARS-CoV-2 is regarded as an important drug target for the treatment of Coronavirus …

An understanding of the interaction between the antibody and its targeted antigen and
knowing of the epitopes are critical for the development of monoclonal antibody drugs …

Adipocyte fatty-acid binding protein (A-FABP) is an important target of drug designs treating
some diseases related to lipid-mediated biology. Molecular dynamics (MD) simulations …

Sol g 2, a major protein found in the venom of the tropical fire ant (Solenopsis geminata), is
well-known for its ability to bind various hydrophobic molecules. In this study, we investigate …

Although the catalytic triad of glutathione peroxidase (GPx) has been well recognized, there
was little evidence for the relevance of the interactions among the triad amino acid residues …

Rational redesign of allosteric protein offers an efficient strategy to develop switchable
biocatalysts. By combining the computational design and protein engineering, a glutathione …

Since its discovery 200 years ago, in 1817, by Jöns Jacob Berzelius (1779–1848), the
element selenium has had a rather chequered relationship with biology and medicine, an …

Drug-resistant Staphylococcus aureus (DRSA) poses a significant global health threat, like
bacteremia, endocarditis, skin, soft tissue, bone, and joint infections. Nowadays, the …