Liposomes: Structure, composition, types, and clinical applications
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …
active hydrophobic and hydrophilic molecules due to their high biocompatibility …
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …
commonly used approach for improving the efficiency of drug and gene delivery to target …
Liposomal drug delivery systems: from concept to clinical applications
The first closed bilayer phospholipid systems, called liposomes, were described in 1965 and
soon were proposed as drug delivery systems. The pioneering work of countless liposome …
soon were proposed as drug delivery systems. The pioneering work of countless liposome …
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …
field has experienced an exponential growth since early 2000's. The path to the …
Liposomes and extracellular vesicles as drug delivery systems: A comparison of composition, pharmacokinetics, and functionalization
L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
Nanoparticle PEGylation for imaging and therapy
Nanoparticles are an essential component in the emerging field of nanomedical imaging
and therapy. When deployed in vivo, these materials are typically protected from the immune …
and therapy. When deployed in vivo, these materials are typically protected from the immune …
Stealth coating of nanoparticles in drug-delivery systems
Nanoparticles (NPs) have emerged as a powerful drug-delivery tool for cancer therapies to
enhance the specificity of drug actions, while reducing the systemic side effects …
enhance the specificity of drug actions, while reducing the systemic side effects …
Liposomal nanomedicine: applications for drug delivery in cancer therapy
F Rommasi, N Esfandiari - Nanoscale Research Letters, 2021 - Springer
The increasing prevalence of cancer, a disease in which rapid and uncontrollable cell
growth causes complication and tissue dysfunction, is one of the serious and tense concerns …
growth causes complication and tissue dysfunction, is one of the serious and tense concerns …
PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
We investigated the in vitro and in vivo properties of DNA/transferrin–polyethylenimine (800
kDa) complexes before and after covalent coupling of poly (ethylene glycol)(PEG). Upon …
kDa) complexes before and after covalent coupling of poly (ethylene glycol)(PEG). Upon …
The journey of a drug-carrier in the body: an anatomo-physiological perspective
Recent advances in chemistry and material sciences have witnessed the emergence of an
increasing number of novel and complex nanosized carriers for the delivery of drugs and …
increasing number of novel and complex nanosized carriers for the delivery of drugs and …