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In vitro assembly, positioning and contraction of a division ring in minimal cells
Constructing a minimal machinery for autonomous self-division of synthetic cells is a major
goal of bottom-up synthetic biology. One paradigm has been the E. coli divisome, with the …
goal of bottom-up synthetic biology. One paradigm has been the E. coli divisome, with the …
Phospholipid synthesis inside phospholipid membrane vesicles
S Eto, R Matsumura, Y Shimane, M Fujimi… - Communications …, 2022 - nature.com
Construction of living artificial cells from genes and molecules can expand our
understanding of life system and establish a new aspect of bioengineering. However, growth …
understanding of life system and establish a new aspect of bioengineering. However, growth …
Nonequilibrium membrane dynamics induced by active protein interactions and chemical reactions: a review
H Noguchi - ChemSystemsChem, 2025 - Wiley Online Library
Biomembranes wrap** cells and organelles are not only the partitions that separate the
insides but also dynamic fields for biological functions accompanied by membrane shape …
insides but also dynamic fields for biological functions accompanied by membrane shape …
Machine learning-aided design and screening of an emergent protein function in synthetic cells
Abstract Recently, utilization of Machine Learning (ML) has led to astonishing progress in
computational protein design, bringing into reach the targeted engineering of proteins for …
computational protein design, bringing into reach the targeted engineering of proteins for …
Engineering spatiotemporal organization and dynamics in synthetic cells
Constructing synthetic cells has recently become an appealing area of research. Decades of
research in biochemistry and cell biology have amassed detailed part lists of components …
research in biochemistry and cell biology have amassed detailed part lists of components …
Phase-space geometry of mass-conserving reaction-diffusion dynamics
Experimental studies of protein-pattern formation have stimulated new interest in the
dynamics of reaction-diffusion systems. However, a comprehensive theoretical …
dynamics of reaction-diffusion systems. However, a comprehensive theoretical …
Transcription and translation in cytomimetic protocells perform most efficiently at distinct macromolecular crowding conditions
MA Vibhute, MH Schaap, RJM Maas… - ACS Synthetic …, 2020 - ACS Publications
The formation of cytomimetic protocells that capture the physicochemical aspects of living
cells is an important goal in bottom-up synthetic biology. Here, we recreated the crowded …
cells is an important goal in bottom-up synthetic biology. Here, we recreated the crowded …
Continuous cell-free replication and evolution of artificial genomic DNA in a compartmentalized gene expression system
In all living organisms, genomic DNA continuously replicates by the proteins encoded in
itself and undergoes evolution through many generations of replication. This continuous …
itself and undergoes evolution through many generations of replication. This continuous …
Time-reversal and parity-time symmetry breaking in non-Hermitian field theories
We study time-reversal symmetry breaking in non-Hermitian fluctuating field theories with
conserved dynamics, comprising the mesoscopic descriptions of a wide range of …
conserved dynamics, comprising the mesoscopic descriptions of a wide range of …
Bulk-surface coupling identifies the mechanistic connection between Min-protein patterns in vivo and in vitro
Self-organisation of Min proteins is responsible for the spatial control of cell division in
Escherichia coli, and has been studied both in vivo and in vitro. Intriguingly, the protein …
Escherichia coli, and has been studied both in vivo and in vitro. Intriguingly, the protein …