Polygenic adaptation: a unifying framework to understand positive selection

N Barghi, J Hermisson, C Schlötterer - Nature Reviews Genetics, 2020 - nature.com
Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …

Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions

S Hoban, JL Kelley, KE Lotterhos… - The American …, 2016 - journals.uchicago.edu
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

Genomics of disease risk in globally diverse populations

D Gurdasani, I Barroso, E Zeggini… - Nature Reviews …, 2019 - nature.com
Risk of disease is multifactorial and can be shaped by socio-economic, demographic,
cultural, environmental and genetic factors. Our understanding of the genetic determinants …

Evolution of crop species: genetics of domestication and diversification

RS Meyer, MD Purugganan - Nature reviews genetics, 2013 - nature.com
Domestication is a good model for the study of evolutionary processes because of the recent
evolution of crop species (< 12,000 years ago), the key role of selection in their origins, and …

Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars

CR Cavanagh, S Chao, S Wang… - Proceedings of the …, 2013 - National Acad Sciences
Domesticated crops experience strong human-mediated selection aimed at develo** high-
yielding varieties adapted to local conditions. To detect regions of the wheat genome subject …

A critical review on applications of the Avrami equation beyond materials science

K Shirzad, C Viney - Journal of the Royal Society …, 2023 - royalsocietypublishing.org
The Johnson–Mehl–Avrami–Kolmogorov (JMAK) formalization, often referred to as the
Avrami equation, was originally developed to describe the progress of phase …

Population genomics of rapid adaptation by soft selective sweeps

PW Messer, DA Petrov - Trends in ecology & evolution, 2013 - cell.com
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …

Robust identification of local adaptation from allele frequencies

T Günther, G Coop - Genetics, 2013 - academic.oup.com
Comparing allele frequencies among populations that differ in environment has long been a
tool for detecting loci involved in local adaptation. However, such analyses are complicated …

Revisiting an old riddle: what determines genetic diversity levels within species?

EM Leffler, K Bullaughey, DR Matute, WK Meyer… - 2012 - journals.plos.org
Understanding why some species have more genetic diversity than others is central to the
study of ecology and evolution, and carries potentially important implications for …

Genomic signatures of selection at linked sites: unifying the disparity among species

AD Cutter, BA Payseur - Nature Reviews Genetics, 2013 - nature.com
Population genetics theory supplies powerful predictions about how natural selection
interacts with genetic linkage to sculpt the genomic landscape of nucleotide polymorphism …