A biological network is complex. A group of critical nodes determines the quality and state of
such a network. Increasing studies have shown that diseases and biological networks are …

Cold and drought are two of the most severe threats affecting the growth and productivity of
the tea plant, limiting its global spread. Both stresses cause osmotic changes in the cells of …

The identification of essential proteins in protein-protein interaction (PPI) networks is of great
significance for understanding cellular processes. With the increasing availability of large …

Essential proteins play an essential role in cell survival and replication. Currently, more and
more computational methods are developed to identify essential proteins, which overcome …

For the survival, development, and reproduction of the organism, understanding the working
process of the cell, disease study, design drugs, etc. essential protein plays a crucial role …

Essential proteins are critical to the development and survival of cells. Identification of
essential proteins is helpful for understanding the minimal set of required genes in a living …

The essential protein detection on protein–protein interaction (PPI) network can not only
promote the research of life science, but also have important applications in disease …

Using combined genetic map**, Illumina sequencing, bioinformatics analyses, and
experimental validation, we identified 60 essential genes from 104 lethal mutations in two …

In this work, we propose a novel centrality metric, referred to as star centrality, which
incorporates information from the closed neighborhood of a node, rather than solely from the …

Motivation As large amounts of biological data continue to be rapidly generated, a major
focus of bioinformatics research has been aimed toward integrating these data to identify …