Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production,
support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate …

The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Heavy metal pollution not only poses a serious threat to both animal growth and public
health, but also to aquatic life. Mitochondria are the first target sites for a variety of heavy …

Abstract Calcium ions (Ca2+) are some of the most versatile signalling molecules, and they
have many physiological functions, prominently including muscle contraction, neuronal …

Ischemic cardiomyopathy (ICM) is a special type of coronary heart disease or an advanced
stage of the disease, which is related to the pathological mechanism of primary dilated …

As a newly emerging hazardous material, airborne nanoplastics are easily inhaled and
accumulated in human and animal alveoli. We previously found that polystyrene …

Abstract Purpose of Review Mitochondria play various roles that are important for cell
function and survival; therefore, significant mitochondrial dysfunction may have chronic …

Mitophagy is an evolutionarily conserved process involving the autophagic targeting and
clearance of mitochondria destined for removal. Recent insights into the complex nature of …

Mitophagy is a highly conserved cellular process that maintains the mitochondrial quantity
by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The …

Disturbed mitochondrial homeostasis contributes to the pathogenesis of cardiac ischemia
reperfusion (IR) injury, although the underlying mechanism remains elusive. Here, we …