Oral mucositis is a common complication of cancer treatment that may negatively impact the
patient's cancer treatment outcome. Despite its frequency and consequences, the lack of …

Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked
clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and …

Background Considerable progress has been made in our understanding of the biological
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …

Purpose Diarrhea is one of the dose limiting toxicity of irinotecan. SN-38 is main irinotecan
metabolite responsible for diarrhea development, which is excreted in glucuronidated form …

Background and Purpose Intestinal mucositis refers to mucosal damage caused by cancer
treatment, and irinotecan is one of the agents most associated with this condition. Focusing …

Chemotherapy-induced diarrhea (CID) is a common and often severe side effect
experienced by colorectal cancer (CRC) patients during their treatment. As chemotherapy …

Mucositis is one of the most common debilitating side effects related to chemotherapy (CT),
radiation therapy (RT), targeted agents and immunotherapy. It is a complex process …

Neurotoxicity is a common side effect of chemotherapy treatment, with unclear molecular
mechanisms. Clinical studies suggest that the most frequent neurotoxic adverse events …

Chemotherapy is still the first line of treatment for most cancer patients. Patients receiving
chemotherapy are generally prone to infections, which result in complications, such as …

Purpose: Colitis-associated colorectal cancer (CAC) poses substantial challenges for
effective treatment. Currently, there is a considerable need for the development of orally …