Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Background Ovarian cancer continues to have a poor prognosis with the majority of women
diagnosed with advanced disease. Therefore, we undertook the UK Collaborative Trial of …

Background Despite early interest in the health effects of polyunsaturated fatty acids (PUFA),
there is still substantial controversy and uncertainty on the evidence linking PUFA to …

Increase in the aging population is a phenomenon all over the world. Maintaining good
functional ability, good mental health, and cognitive function in the absence of severe …

The complex biological mechanisms underlying human brain aging remain incompletely
understood. This study investigated the genetic architecture of three brain age gaps (BAG) …

The role of fatty acids (FAs) in primary prevention of coronary artery disease (CAD) is highly
debated, and the modification effect by genetic risk profiles remains unclear. Here, we report …

Background Evidence on the association between virgin olive oil (OO) and mortality is
limited since no attempt has previously been made to discern about main OO varieties …

Background Omega-3 has been extensively studied for its cardiovascular disease (CVD)
benefits. However, the results of this evidence are inconsistent. Therefore, in this study …

Aims Associations of saturated and unsaturated fatty acids (FAs) with cardiovascular
disease (CVD) remain controversial. We therefore aimed to investigate the prospective …

Page 1 Saturated fat and trans-fat intakes and their replacement with other macronutrients A
systematic review and meta-analysis of prospective observational studies Andrew N Reynolds …