With the rapidly aging human population, age-related cognitive decline and dementia are
becoming increasingly prevalent worldwide. Aging is considered the main risk factor for …

Background Diabetic cognitive dysfunction (DCD) is one of the most insidious complications
of type 2 diabetes mellitus, which can seriously affect the ability to self‐monitoring of blood …

Accumulating evidence suggests that gut microbiota as a critical mediator of gut-brain axis
plays an important role in human health. Altered gut microbial profiles have been implicated …

Fiber intake is associated with a lower risk for Alzheimer´ s disease (AD) in older adults.
Intake of plant-based diets rich in soluble fiber promotes the production of short-chain fatty …

Maternal obesity disturbs brain–gut–microbiota interactions and induces negative affect in
the offspring, but its impact on gut and brain metabolism in the offspring (F1) are unknown …

In the central nervous system (CNS), glial cells, such as microglia and astrocytes, are
normally associated with support roles including contributions to energy metabolism …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal
neurodegenerative disorders often co-occurring in the same patient, a feature that suggests …

Astrocytes provide metabolic support to neurons, maintain ionic and water homeostasis, and
uptake and recycle neurotransmitters. After exposure to the prototypical PAMP …

Astrocytes protect neurons by modulating neuronal function and survival. Astrocytes support
neurons in several ways. They provide energy through the astrocyte-neuron lactate shuttle …

Astrocytes are essential for maintaining the homeostasis of the central nervous system
(CNS). Astrocytic dysfunction has been implicated in the progression of several …