Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …

Gastrodin, a phenolic glycoside, is a prominent component of Gastrodia elata, which is
renowned for its sedative, hypnotic, anticonvulsant, and neuroprotective activities …

Transcriptome‐wide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …

Understanding the complex network that regulates transcription elongation requires the
quantitative analysis of RNA polymerase II (Pol II) activity in a wide variety of regulatory …

Key to our ability to increase recombinant protein production through secretion is a better
understanding of the pathways that interact to translate, process and export mature proteins …

Background The start and end sites of messenger RNAs (TSSs and TESs) are highly
regulated, often in a cell-type-specific manner. Yet the contribution of transcript diversity in …

Histones are substrates of the SUMO (small ubiquitin-like modifier) conjugation pathway.
Several reports suggest histone sumoylation affects transcription negatively, but …

Colorectal cancers have become the second leading cause of cancer-related deaths. In
particular, acquired chemoresistance and metastatic lesions occurring in colorectal cancer …

Impaired oxygen homeostasis is a frequently encountered pathophysiological factor in
multiple complex diseases, including cardiovascular disease and cancer. While the …

Quiescence, the temporary and reversible arrest of cell growth, is a fundamental biological
process. However, the lack of standardization in terms of reporting the experimental details …