Background Sepsis causes multiple organ dysfunctions and raises mortality and morbidity
rates through a dysregulated host response to infection. Despite the growing research …

Aim Bortezomib is a proteasome inhibitor antineoplastic agent that was the first to be
approved for cancer treatment. One of bortezomib's most prominent dose-limiting effects is …

Arsenic is a toxic environmental pollutant heavy metal, and one of its critical target tissues in
the body is the liver. Carvacrol is a natural phytocompound that stands out with its …

Paclitaxel (PTX), which is actively used in the treatment of many types of cancer, has a toxic
effect by causing increased oxidative stress in testicular tissues. Naringin (NRG) is a natural …

Approximately 20 million new cancer cases have occurred worldwide, and dose limitation
occurs because of the liver and kidney toxicity of chemotherapeutic agents. Inflammation …

Aim Tramadol (TRM), a widely used opioid analgesic for moderate to severe pain, is
associated with liver and kidney toxicity at high doses or prolonged use. This study …

Ovarian ischemia is a pathological condition that usually occurs due to ovarian torsion,
resulting in the interruption of blood supply to the ovaries and oxygen deficiency. Silymarin …

Testicular dysfunction is a significant long-term side effect of the chemotherapeutic drug
cisplatin (CDDP), primarily due to DNA damage and oxidative stress. Lisinopril (LSP), an …

Objective (s): Diclofenac (Diclo) is a therapeutic agent used in the treatment of pain and
inflammatory diseases, but it is also toxic to the human body. Morin is a flavonoid found …

Aim Testicular torsion, which occurs when the testicle rotates around the axis of the
spermatic cord, is a serious cause of hospital admission, mostly in newborns and children …