Photodynamic therapy—current limitations and novel approaches
Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …
Photodynamic Therapy for the Treatment and Diagnosis of Cancer–A Review of the Current Clinical Status
Photodynamic therapy (PDT) has been used as an anti-tumor treatment method for a long
time and photosensitizers (PS) can be used in various types of tumors. Originally, light is an …
time and photosensitizers (PS) can be used in various types of tumors. Originally, light is an …
Clinical development and potential of photothermal and photodynamic therapies for cancer
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …
of tumour ablation for numerous cancer indications. Two main approaches are available …
Recent advances of AIE light-up probes for photodynamic therapy
As a new non-invasive treatment method, photodynamic therapy (PDT) has attracted great
attention in biomedical applications. The advantages of possessing fluorescence for …
attention in biomedical applications. The advantages of possessing fluorescence for …
Long wavelength–emissive Ru (II) metallacycle–based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment
Y Xu, C Li, X Ma, W Tuo, L Tu, X Li… - Proceedings of the …, 2022 - National Acad Sciences
Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
Fluorescent probes for the detection of disease-associated biomarkers
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …
biology and medicine. The ability to detect intracellular species and monitor physiological …
Reactive oxygen species (ROS)-based nanomedicine
B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …
Complementing cancer photodynamic therapy with ferroptosis through iron oxide loaded porphyrin-grafted lipid nanoparticles
Nanomaterials that combine multimodality imaging and therapeutic functions within a single
nanoplatform have drawn extensive attention for molecular medicines and biological …
nanoplatform have drawn extensive attention for molecular medicines and biological …
Light-induced control of protein destruction by opto-PROTAC
By hijacking endogenous E3 ligase to degrade protein targets via the ubiquitin-proteasome
system, PROTACs (PRoteolysis TArgeting Chimeras) provide a new strategy to inhibit …
system, PROTACs (PRoteolysis TArgeting Chimeras) provide a new strategy to inhibit …
Catalase-integrated hyaluronic acid as nanocarriers for enhanced photodynamic therapy in solid tumor
Photodynamic therapy (PDT) as a treatment method has many advantages such as minimal
invasiveness, repeatable dosage, and low systemic toxicity. Issues with conventional PDT …
invasiveness, repeatable dosage, and low systemic toxicity. Issues with conventional PDT …