Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …

Precise estimates of epileptogenic zone networks (EZNs) are crucial for planning
intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual …

Individuals with drug-resistant focal epilepsy are candidates for surgical treatment as a
curative option. Before surgery can take place, the patient must have a presurgical …

Epilepsy is a common disorder characterized by recurrent seizures. An overwhelming
majority of people with epilepsy regard the unpredictability of seizures as a major issue …

Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …

Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

The human brain has the capacity to rapidly change state, and in epilepsy these state
changes can be catastrophic, resulting in loss of consciousness, injury and even death …