Current perspectives on corneal collagen crosslinking (CXL)

SK Subasinghe, KC Ogbuehi, GJ Dias - Graefe's Archive for Clinical and …, 2018 - Springer
Corneal collagen crosslinking has revolutionized the treatment of keratoconus and post-
refractive corneal ectasia in the past decade. Corneal crosslinking with riboflavin and …

Corneal cross-linking: the science beyond the myths and misconceptions

RS Rubinfeld, C Caruso, C Ostacolo - Cornea, 2019 - journals.lww.com
Purpose: There has been a recent explosion in the variety of techniques used to accomplish
corneal cross-linking (CXL) for the treatment of ectatic corneal diseases. To understand the …

[HTML][HTML] Riboflavin concentrations at the endothelium during corneal cross-linking in humans

TG Seiler, A Batista, BE Frueh… - … ophthalmology & visual …, 2019 - tvst.arvojournals.org
Purpose: To determine the riboflavin concentration in the posterior corneal stroma,
Descemet's membrane, and endothelium prior to UV irradiation in corneal cross-linking …

[HTML][HTML] Biomechanics of ophthalmic crosslinking

BJ Blackburn, AM Rollins… - … Vision Science & …, 2021 - jov.arvojournals.org
Crosslinking involves the formation of bonds between polymer chains, such as proteins. In
biological tissues, these bonds tend to stiffen the tissue, making it more resistant to …

Evaluating the safety and efficacy of epi-off corneal cross-linking in patients with thin corneas due to keratectasia

A Nieuwsma, BL Vander Zee… - Therapeutic …, 2023 - journals.sagepub.com
Background: Corneal cross-linking (CXL) is a safe and effective procedure for slowing
keratectasia progression in eyes with a corneal thickness of at least 400 µm. Limited …

Combined analysis of safety and optimal efficacy in UV-light-activated corneal collagen crosslinking

JT Lin - Ophthalmology Research: An International …, 2016 - open.journal4submit.com
Aims: To analyze the combined factors for safety and optimal efficacy for UV-light-initiated
corneal collagen cross-linking (CXL). Study Design: Modeling and analysis of CXL. Place …

Multi modal imaging in corneal edema after corneal collagen cross-linking (CXL); a case-based literature review

M Soleimani, Z Ebrahimi, MY Moghadam… - BMC …, 2021 - Springer
Background Keratoconus (KCN) is a common ectatic disorder of the cornea. Corneal
collagen cross-linking (CXL) is used as an effective option to slowdown the disease …

Essential role of ultraviolet radiation in the decrease of corneal endothelial cell density caused by pterygium

X Li, Y Dai, W Xu, J Xu - Eye, 2018 - nature.com
Purpose To investigate the essential role of ultraviolet (UV) radiation in the decrease of
corneal endothelial cell density (ECD) caused by pterygium. Methods In this retrospective …

Is Pterygium Morphology Related to Loss of Corneal Endothelial Cells? A Cross-Sectional Study

SBH Zaidi, W Ali Khan - Clinical Ophthalmology, 2021 - Taylor & Francis
Purpose To determine the difference in mean corneal endothelial cell density (CECD)
between the healthy and diseased eyes of the patients with unilateral pterygium with …

Efficacy and z* formula for minimum corneal thickness in ultraviolet light cross-linking

J Lin - Cornea, 2017 - journals.lww.com
To the Editor: In their recent article, Caruso et al1 developed a mathematical model to define
the minimum corneal safety thickness in corneal cross-linking (CXL) by a numerical solution …