Kidney metabolism and acid–base control: back to the basics

PH Imenez Silva, N Mohebbi - Pflügers Archiv-European Journal of …, 2022‏ - Springer
Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

Metabolic acidosis in chronic kidney disease: mere consequence or also culprit?

C Kuhn, N Mohebbi, A Ritter - Pflügers Archiv-European Journal of …, 2024‏ - Springer
Metabolic acidosis is a frequent complication in non-transplant chronic kidney disease
(CKD) and after kidney transplantation. It occurs when net endogenous acid production …

Metabolic Acidosis in CKD: Pathogenesis, Adverse Effects, and Treatment Effects

KL Raphael - International Journal of Molecular Sciences, 2024‏ - mdpi.com
Metabolic acidosis is a frequent complication of chronic kidney disease and is associated
with a number of adverse outcomes, including worsening kidney function, poor …

[HTML][HTML] Diet and metabolism in CKD-related metabolic acidosis

A Vincent-Johnson, B Davy, JJ Scialla - Seminars in Nephrology, 2023‏ - Elsevier
Metabolic acidosis is a common complication in patients with chronic kidney disease that
occurs when the daily nonvolatile acid load produced in metabolism cannot be excreted fully …

[HTML][HTML] Phosphorus intake and potential dietary influences examined via 24-Hour urinary biomarker measurements in German children and adolescents over 3 …

LP Franco, SM Derakhshandeh-Rishehri, Y Hua… - Journal of the Academy …, 2024‏ - Elsevier
Background Increases in phosphorus intake have been observed over the past years in
adult populations. However, biomarker-based data are lacking on whether or not …

Beyond the urine anion gap: in support of the direct measurement of urinary ammonium

J Uribarri, DS Goldfarb, KL Raphael, JL Rein… - American Journal of …, 2022‏ - Elsevier
Ammonium is a major urinary buffer that is necessary for the normal excretion of the daily
acid load. Its urinary rate of excretion (UNH 4) may be increased several fold in the presence …

Diet and hypertension

E Tantisattamo, K Kalantar-Zadeh - Hypertension, 2024‏ - Elsevier
Pharmacologic intervention is one of the cornerstones of management for hypertension.
However, potential adverse drug reactions, drug-drug interaction, as well as safety and …

Acid-mediated kidney injury across the spectrum of metabolic acidosis

NPG Ravikumar, AC Pao, KL Raphael - Advances in chronic kidney …, 2022‏ - Elsevier
Metabolic acidosis affects about 15% of patients with chronic kidney disease. As kidney
function declines, the kidneys progressively fail to eliminate acid, primarily reflected by a …

Nutritional and dietary interventions to prolong renal allograft survival after kidney transplantation

E Tantisattamo, K Kalantar-Zadeh… - Current opinion in …, 2022‏ - journals.lww.com
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[HTML][HTML] Prevalence rate of proteinuria and metabolic acidosis among kidney transplant recipients in a tertiary teaching hospital and its relationship to dietary intake

WP Lau, KP Ng, SS Ganapathy, PC Tah… - Transplantation …, 2022‏ - Elsevier
Background Proteinuria and metabolic acidosis adversely affect long term renal allograft
outcome and are highly prevalent in reported studies. The role of dietary intake in …