Multiple sclerosis: time for early treatment with high-efficacy drugs
This review addresses current changes in the approach to treating patients with multiple
sclerosis (MS). The widely practiced approach of utilizing agents with lower treatment …
sclerosis (MS). The widely practiced approach of utilizing agents with lower treatment …
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: methotrexate, alkylating agents, biologics, and small molecule inhibitors
In solid organ transplant recipients, skin cancer risk associated with posttransplant
immunosuppression has been well-described, and screening practices generally reflect …
immunosuppression has been well-described, and screening practices generally reflect …
Novel potential pharmacological applications of dimethyl fumarate—an overview and update
G Bresciani, F Manai, S Davinelli, P Tucci… - Frontiers in …, 2023 - frontiersin.org
Dimethyl fumarate (DMF) is an FDA-approved drug for the treatment of psoriasis and
multiple sclerosis. DMF is known to stabilize the transcription factor Nrf2, which in turn …
multiple sclerosis. DMF is known to stabilize the transcription factor Nrf2, which in turn …
Adverse drug reactions with drugs used in multiple sclerosis: an analysis from the Italian pharmacovigilance database
MA Barbieri, EE Sorbara, A Battaglia… - Frontiers in …, 2022 - frontiersin.org
Given the importance of inflammation at the onset of multiple sclerosis (MS), therapy is
mainly based on the use of anti-inflammatory drugs including disease modifying therapies …
mainly based on the use of anti-inflammatory drugs including disease modifying therapies …
Clinical use of dimethyl fumarate in multiple sclerosis treatment: an update to include China, using a modified Delphi method
R Gold, M Barnett, A Chan, H Feng… - Therapeutic …, 2023 - journals.sagepub.com
Dimethyl fumarate (DMF) is a widely used oral disease-modifying therapy for multiple
sclerosis (MS). Its efficacy and safety profiles are supported by over a decade of experience …
sclerosis (MS). Its efficacy and safety profiles are supported by over a decade of experience …
Co-occurrence of glioma and multiple sclerosis: prevailing theories and emerging therapies
Though the concurrence of primary brain tumors and multiple sclerosis (MS) is exceedingly
rare, instances have been noted in the literature as early as 1949. Given these observations …
rare, instances have been noted in the literature as early as 1949. Given these observations …
The safety and efficacy of fingolimod: Real-world data from a long-term, non-interventional study on the treatment of RRMS patients spanning up to 5 years from …
T Biernacki, D Sandi, J Füvesi, Z Fricska-Nagy… - Plos one, 2022 - journals.plos.org
Background Fingolimod was approved and reimbursed by the healthcare provider in
Hungary for the treatment of highly active relapsing-remitting multiple sclerosis (RRMS) in …
Hungary for the treatment of highly active relapsing-remitting multiple sclerosis (RRMS) in …
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies
S Räuber, A Schulte-Mecklenbeck, A Willison… - Journal of …, 2024 - Springer
Background Immune dysregulation is a hallmark of autoimmune diseases of the central
nervous system (CNS), characterized by an excessive immune response, and primary CNS …
nervous system (CNS), characterized by an excessive immune response, and primary CNS …
Exploring the role of sex hormones and gender diversity in multiple sclerosis
Sex and sex hormones are thought to influence multiple sclerosis (MS) through effects on
inflammation, myelination and neurodegeneration, and exogenous hormones have been …
inflammation, myelination and neurodegeneration, and exogenous hormones have been …
Multiple sclerosis and breast cancer risk: a meta-analysis of observational and Mendelian randomization studies
T Fang, Z Zhang, H Zhou, W Wu, L Zou - Frontiers in Neuroinformatics, 2023 - frontiersin.org
Background Several observational studies have explored the relationships between multiple
sclerosis (MS) and breast cancer; however, whether an association exists remains unknown …
sclerosis (MS) and breast cancer; however, whether an association exists remains unknown …