Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Epithelial–mesenchymal transition (EMT) is a crucial embryonic programme that is executed
by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and …

The epithelial-mesenchymal transition (EMT) is an essential mechanism in embryonic
development and tissue repair. EMT also contributes to the progression of disease …

The molecular mechanisms that underlie tumour progression are still poorly understood, but
recently our knowledge of particular aspects of some of these processes has increased …

Invasion, metastasis and therapy resistance are the major cause of cancer‐associated
deaths, and the EMT‐inducing transcription factor ZEB 1 is a crucial stimulator of these …

The deployment of a cell's genetic program in a multicellular organism must be tightly
controlled for the sake of the organism as a whole. Over the past 20 years the transforming …

Transcriptional downregulation of E-cadherin appears to be an important event in the
progression of various epithelial tumors. SIP1 (ZEB-2) is a Smad-interacting, multi-zinc …

Epithelial to mesenchymal transition occurs during embryologic development to allow tissue
remodeling and is proposed to be a key step in the metastasis of epithelial-derived tumors …

Loss of expression of the E-cadherin cell-cell adhesion molecule is important in carcinoma
development and progression. Because previous data suggest that loss of E-cadherin …

The adherens junction (AJ) is an element of the cell–cell junction in which cadherin
receptors bridge the neighboring plasma membranes via their homophilic interactions …