The most fundamental feature of cellular form is size, which sets the scale of all cell
biological processes. Growth, form, and function are all necessarily linked in cell biology, but …

Live-cell microscopy is a powerful tool that can reveal cellular behavior as well as the
underlying molecular processes. A key advantage of microscopy is that by visualizing …

Schizosaccharomyces pombe is a widely used model organism to study many aspects of
eukaryotic cell physiology. Its popularity as an experimental system partially stems from the …

Cells self-organize using reaction-diffusion and fluid-flow principles. Whether bulk
membrane flows contribute to cell patterning has not been established. Here, using …

Cytokinesis is the final stage of cell division cycle when cellular constituents are separated
to produce two daughter cells. This process is driven by the formation and constriction of a …

In many organisms, positive and negative signals cooperate to position the division site for
cytokinesis. In the rod-shaped fission yeast Schizosaccharomyces pombe, symmetric …

Fission yeast cells divide at a similar cell length with little variation about the mean. This is
thought to be the result of a control mechanism that senses size and corrects for any …

In the context of animal or plant development, we tend to think of cells as small, simple,
building blocks, such that complex patterns or shapes can only be constructed from large …

To enter into mitosis, cells must shut off the cell cycle inhibitor Wee1. SAD family protein
kinases regulate Wee1 signaling in yeast and humans. In Schizosaccharomyces pombe …

The notion that graded distributions of signals underlie the spatial organization of biological
systems has long been a central pillar in the fields of cell and developmental biology. During …