Intravenous administration of drugs is a widely used cancer therapy approach. However, the
efficacy of these drugs is often hindered by various biological barriers, including circulation …

Drug delivery systems are becoming increasingly utilized; however, a major challenge in
this field is the insufficient target of tissues or cells. Although efforts with engineered …

Tumor recurrence and metastasis are important causes of death in breast cancer patients
after surgery. However, the nanomedicines are often difficult to accumulate and retain in …

Cationic materials currently serve as the primary materials for siRNA encapsulation;
however, inherent cationic toxicity and limited shelf‐life have hindered their clinical …

The antitumor effects of conventional drug carriers are often attenuated and limited in
application by biological barriers associated with tumor heterogeneity and resistance …

Immunotherapy has recently emerged as a promising therapeutic modality for the treatment
of various diseases such as cancer, inflammation, autoimmune diseases, and infectious …

Introduction Cancer-related drug expenses are rising with the increasing cancer incidence
and cost may represent a severe challenge for drug access for patients with cancer …

In addition to hemostasis and coagulation, years of studies have proved that platelets are
involved in the whole process of tumor progression, including tumor invasion, intravasation …

Multifunctional targeted drug delivery systems have been explored as a novel cancer
treatment strategy to overcome limitations of traditional chemotherapy. The combination of …

Controllable and precise delivery of therapeutic agents is critical for effective tumor therapy.
However, tumor targeting and the deep penetration of drugs remain among the most …