Vestibular compensation: the neuro-otologist's best friend

M Lacour, C Helmchen, PP Vidal - Journal of neurology, 2016 - Springer
Why vestibular compensation (VC) after an acute unilateral vestibular loss is the neuro-
otologist's best friend is the question at the heart of this paper. The different plasticity …

The balance of sleep: role of the vestibular sensory system

S Besnard, B Tighilet, C Chabbert, M Hitier… - Sleep medicine …, 2018 - Elsevier
The vestibular system encodes linear and angular head motion supporting numerous
functions from gaze stabilization and postural control, to high-level cortical functions …

Adult neurogenesis promotes balance recovery after vestibular loss

B Tighilet, C Chabbert - Progress in Neurobiology, 2019 - Elsevier
A phenomenon called vestibular compensation occurs after peripheral vestibular loss. This
process involves a mosaic of profound structural rearrangements within the vestibular …

Sequential [18F]FDG µPET whole-brain imaging of central vestibular compensation: a model of deafferentation-induced brain plasticity

A Zwergal, J Schlichtiger, G **ong, R Beck… - Brain Structure and …, 2016 - Springer
Unilateral inner ear damage is followed by a rapid behavioural recovery due to central
vestibular compensation. In this study, we utilized serial [18 F] Fluoro-deoxyglucose ([18 F] …

Thyroid Axis and Vestibular Physiopathology: From Animal Model to Pathology

G Rastoldo, B Tighilet - International journal of molecular sciences, 2023 - mdpi.com
A recent work of our group has shown the significant effects of thyroxine treatment on the
restoration of postural balance function in a rodent model of acute peripheral vestibulopathy …

Comparative analysis of pharmacological treatments with N-acetyl-DL-leucine (Tanganil) and its two isomers (N-acetyl-L-leucine and N-acetyl-D-leucine) on …

B Tighilet, J Leonard, L Bernard-Demanze… - European Journal of …, 2015 - Elsevier
Head roll tilt, postural imbalance and spontaneous nystagmus are the main static vestibular
deficits observed after an acute unilateral vestibular loss (UVL). In the UVL cat model, these …

BDNF signaling promotes vestibular compensation by increasing neurogenesis and remodeling the expression of potassium-chloride cotransporter KCC2 and …

S Dutheil, I Watabe, K Sadlaoud, A Tonetto… - Journal of …, 2016 - jneurosci.org
Reactive cell proliferation occurs rapidly in the cat vestibular nuclei (VN) after unilateral
vestibular neurectomy (UVN) and has been reported to facilitate the recovery of posturo …

Adult and endemic neurogenesis in the vestibular nuclei after unilateral vestibular neurectomy

G Rastoldo, N El Mahmoudi, E Marouane… - Progress in …, 2021 - Elsevier
We previously revealed adult reactive neurogenesis in deafferented vestibular nuclei
following unilateral vestibular neurectomy (UVN) in the feline model. We recently replicated …

Surgical techniques and functional evaluation for vestibular lesions in the mouse: unilateral labyrinthectomy (UL) and unilateral vestibular neurectomy (UVN)

F Simon, D Pericat, C Djian, D Fricker, F Denoyelle… - Journal of …, 2020 - Springer
Objective Unilateral labyrinthectomy (UL) and unilateral vestibular neurectomy (UVN) are
two surgical methods to produce vestibular lesions in the mouse. The objective of this study …

[HTML][HTML] L-Thyroxine improves vestibular compensation in a rat model of acute peripheral vestibulopathy: Cellular and behavioral aspects

G Rastoldo, E Marouane, N El-Mahmoudi, D Péricat… - Cells, 2022 - mdpi.com
Unilateral vestibular lesions induce a vestibular syndrome, which recovers over time due to
vestibular compensation. The therapeutic effect of L-Thyroxine (L-T4) on vestibular …