Fetal alcohol spectrum disorders

S Popova, ME Charness, L Burd, A Crawford… - Nature reviews Disease …, 2023 - nature.com
Alcohol readily crosses the placenta and may disrupt fetal development. Harm from prenatal
alcohol exposure (PAE) is determined by the dose, pattern, timing and duration of exposure …

Microglia autophagy in ischemic stroke: A double-edged sword

L Peng, G Hu, Q Yao, J Wu, Z He, BYK Law… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke (IS) is one of the major types of cerebrovascular diseases causing
neurological morbidity and mortality worldwide. In the pathophysiological process of IS …

The impact of oxidative stress on the epigenetics of Fetal Alcohol Spectrum Disorders

S Terracina, L Tarani, M Ceccanti, M Vitali, S Francati… - Antioxidants, 2024 - mdpi.com
Fetal alcohol spectrum disorders (FASD) represent a continuum of lifelong impairments
resulting from prenatal exposure to alcohol, with significant global impact. The “spectrum” of …

Epigenetics and neuroinflammation associated with neurodevelopmental disorders: a microglial perspective

M Komada, Y Nishimura - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Neuroinflammation is a cause of neurodevelopmental disorders such as autism spectrum
disorders, fetal alcohol syndrome, and cerebral palsy. Converging lines of evidence from …

Identifying prenatal alcohol exposure and children affected by it: A review of biomarkers and screening tools

JA Kable, KL Jones - Alcohol research: current reviews, 2023 - pmc.ncbi.nlm.nih.gov
PURPOSE: Early identification of prenatal alcohol exposure (PAE) and of those in need of
services resulting from this exposure is an important public health concern. This study …

Impact of two different rodent diets on maternal ethanol consumption, serum ethanol concentration and pregnancy outcome measures

S Davies, DE Nelson, S Shrestha, DD Savage - Alcohol, 2023 - Elsevier
Recent studies report varying levels of ethanol consumption by rodents maintained on
different commercially available laboratory diets. As varied ethanol consumption by dams …

[HTML][HTML] Epigenomic and other evidence for cannabis-induced aging contextualized in a synthetic epidemiologic overview of cannabinoid-related teratogenesis and …

AS Reece, GK Hulse - … Journal of Environmental Research and Public …, 2022 - mdpi.com
Background: Twelve separate streams of empirical data make a strong case for cannabis-
induced accelerated aging including hormonal, mitochondriopathic, cardiovascular …

A pilot investigation of differential hydroxymethylation levels in patient-derived neural stem cells implicates altered cortical development in bipolar disorder

A Kumar, MZ Kos, D Roybal, MA Carless - Frontiers in psychiatry, 2023 - frontiersin.org
Introduction Bipolar disorder (BD) is a chronic mental illness characterized by recurrent
episodes of mania and depression and associated with social and cognitive disturbances …

Patterns of cannabis-and substance-related congenital general anomalies in Europe: a geospatiotemporal and causal inferential study

AS Reece, GK Hulse - Pediatric Reports, 2023 - mdpi.com
Introduction: Recent series of congenital anomaly (CA) rates (CARs) have showed the close
and epidemiologically causal relationship of cannabis exposure to many CARs. We …

Expression quantitative trait methylation analysis identifies whole blood molecular footprint in fetal alcohol spectrum disorder (FASD)

IM Krzyzewska, P Lauffer, AN Mul… - International Journal of …, 2023 - mdpi.com
Fetal alcohol spectrum disorder (FASD) encompasses neurodevelopmental disabilities and
physical birth defects associated with prenatal alcohol exposure. Previously, we attempted …