The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Esophageal squamous-cell carcinoma (ESCC) develops through multistage epithelial
cancer formation, ie, from normal epithelium, low-and high-grade intraepithelial neoplasia to …

Oral cancer (OC) is a devastating disease that takes the lives of lots of people globally every
year. The current spectrum of treatment modalities does not meet the needs of the patients …

Abstract Background Tyrosine kinase inhibitors (TKIs) such as sunitinib are multitarget
antiangiogenic agents in clear cell renal cell carcinoma (ccRCC). They are widely used in …

Circulating extracellular vesicles (EVs) were recognized as a promising source of diagnostic
biomarker. However, there are limited studies published in this area, partly due to the limited …

Esophageal carcinoma stem cells (ECSCs) are responsible for the initiation and therapy-
resistance of esophageal cancer. Nutrient sensor O-GlcNAc transferase (OGT) promoted the …

Fibroblasts in the tumor microenvironment, known as cancer-associated fibroblasts (CAFs),
promote the migration, invasion, and metastasis of cancer cells when they are activated …

Esophageal squamous cell carcinoma (ESCC) is one of the most common and aggressive
malignancies in China. Cancer‐associated fibroblasts (CAFs) can actively communicate …

Hepatocellular carcinoma (HCC) is the most commonmalignancy. Exsome plays a
significant role in the elucidation of signal transduction pathways between hepatoma cells …