Clostridium difficile infection

J Czepiel, M Dróżdż, H Pituch, EJ Kuijper… - European Journal of …, 2019 - Springer
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

Understanding Clostridium difficile colonization

MJT Crobach, JJ Vernon, VG Loo… - Clinical microbiology …, 2018 - Am Soc Microbiol
Clostridium difficile is the main causative agent of antibiotic-associated and health care-
associated infective diarrhea. Recently, there has been growing interest in alternative …

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for …

LC McDonald, DN Gerding, S Johnson… - Clinical infectious …, 2018 - academic.oup.com
Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Longitudinal genomic surveillance of carriage and transmission of Clostridioides difficile in an intensive care unit

A Miles-Jay, ES Snitkin, MY Lin, T Shimasaki… - Nature Medicine, 2023 - nature.com
Despite enhanced infection prevention efforts, Clostridioides difficile remains the leading
cause of healthcare-associated infections in the United States. Current prevention strategies …

[HTML][HTML] European Society of Clinical Microbiology and Infectious Diseases: update of the diagnostic guidance document for Clostridium difficile infection

MJT Crobach, T Planche, C Eckert, F Barbut… - Clinical microbiology …, 2016 - Elsevier
Abstract In 2009 the first European Society of Clinical Microbiology and Infectious Diseases
(ESCMID) guideline for diagnosing Clostridium difficile infection (CDI) was launched. Since …

Effects of control interventions on Clostridium difficile infection in England: an observational study

KE Dingle, X Didelot, TP Quan, DW Eyre… - The Lancet Infectious …, 2017 - thelancet.com
Summary Background The control of Clostridium difficile infections is an international clinical
challenge. The incidence of C difficile in England declined by roughly 80% after 2006 …

Diversity and evolution in the genome of Clostridium difficile

DR Knight, B Elliott, BJ Chang… - Clinical microbiology …, 2015 - Am Soc Microbiol
Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Clostridium difficile – From Colonization to Infection

H Schaeffler, A Breitrueck - Frontiers in microbiology, 2018 - frontiersin.org
Clostridium difficile is the most frequent cause of nosocomial antibiotic-associated diarrhea.
The incidence of C. difficile infection (CDI) has been rising worldwide with subsequent …

Colonization with toxinogenic C. difficile upon hospital admission, and risk of infection: a systematic review and meta-analysis

IM Zacharioudakis, FN Zervou, EE Pliakos… - Official journal of the …, 2015 - journals.lww.com
Objectives: It has been suggested that colonization withC. difficileprotects from infection.
Nevertheless, the association between carriage of toxinogenic strains and ensuingC …

Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011

CW Knetsch, TR Connor, A Mutreja… - …, 2014 - eurosurveillance.org
Farm animals are a potential reservoir for human Clostridium difficile infection (CDI),
particularly PCR ribotype 078 which is frequently found in animals and humans. Here, whole …