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Discerning molecular interactions: a comprehensive review on biomolecular interaction databases and network analysis tools
Computational analysis of biomolecular interaction networks is now gaining a lot of
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …
Analyzing protein–protein interaction networks
The advent of the “omics” era in biology research has brought new challenges and requires
the development of novel strategies to answer previously intractable questions. Molecular …
the development of novel strategies to answer previously intractable questions. Molecular …
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
Abstract GeneMANIA (http://www. genemania. org) is a flexible, user-friendly web interface
for generating hypotheses about gene function, analyzing gene lists and prioritizing genes …
for generating hypotheses about gene function, analyzing gene lists and prioritizing genes …
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …
[HTML][HTML] A census of human soluble protein complexes
Cellular processes often depend on stable physical associations between proteins. Despite
recent progress, knowledge of the composition of human protein complexes remains limited …
recent progress, knowledge of the composition of human protein complexes remains limited …
MINT, the molecular interaction database: 2012 update
Abstract The Molecular INTeraction Database (MINT, http://mint. bio. uniroma2. it/mint/) is a
public repository for protein–protein interactions (PPI) reported in peer-reviewed journals …
public repository for protein–protein interactions (PPI) reported in peer-reviewed journals …
Reactome: a database of reactions, pathways and biological processes
Abstract Reactome (http://www. reactome. org) is a collaboration among groups at the
Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University …
Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University …
Pathway Commons, a web resource for biological pathway data
Abstract Pathway Commons (http://www. pathwaycommons. org) is a collection of publicly
available pathway data from multiple organisms. Pathway Commons provides a web-based …
available pathway data from multiple organisms. Pathway Commons provides a web-based …
ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional
interactions from heterogeneous interaction data resources. Physical protein interactions …
interactions from heterogeneous interaction data resources. Physical protein interactions …
Phospho. ELM: a database of phosphorylation sites—update 2011
The Phospho. ELM resource (http://phospho. elm. eu. org) is a relational database designed
to store in vivo and in vitro phosphorylation data extracted from the scientific literature and …
to store in vivo and in vitro phosphorylation data extracted from the scientific literature and …