DNA family shuffling was used to create chimeric lipase B proteins with improved activity
toward the hydrolysis of diethyl 3‐(3′, 4′‐dichlorophenyl) glutarate (DDG). Three …

Describing the essential steps in the development of biocatalytic processes from concept to
completion, this carefully integrated text combines the fundamentals of biocatalysis with …

Sodium borohydride reduction of 3‐chloro‐1‐(2‐thienyl)‐1‐propanone gave the
corresponding racemic alcohol which was kinetically resolved with lipase B from Candida …

Agarose gels coated with a dense layer of polyethylenimine (PEI-agarose containing
1000μmol of ionised groups per wet gram of support) are able to adsorb proteins under a …

A comparison is carried out of the E-values recorded in the lipase-catalyzed resolution of a
series of secondary aryl–alkyl alcohols with enol esters versus succinic anhydride. Whereas …

Sugar-based polyesters derived from sorbitol and isohexides were obtained via solvent-free
enzymatic catalysis. Pendant hydroxyl groups, coming from the sorbitol units, were present …

(+)-Goniothalamin has been synthesized by lipase catalyzed resolution of (1E)-1-
phenylhexa-1, 5-dien-3-ol using vinyl acrylate as acyl donor followed by ring closing …

In the case of such reactions as ester synthesis, water is produced during the reaction.
Because these reactions are carried out in hydrophobic solvents an additional (water) phase …

Efficient methods for kinetic resolution of 1‐phenoxy‐2‐butanol, 1‐phenylmethoxy‐2‐
butanol, and 1‐phenoxy‐2‐pentanol were developed using lipase B from Candida …

Kinetic resolution of racemic 1-azido-3-aryloxy-2-propanols 1a–g was performed using
supported lipase of Candida antarctica-B (Novozym® SP 435) in toluene at 4° C with …