The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Multiple “omics” approaches have emerged as successful technologies for plant systems
over the last few decades. Advances in next-generation sequencing (NGS) have paved a …

Structural biologists have traditionally approached cellular complexity in a reductionist
manner in which the cellular molecular components are fractionated and purified before …

Established methods for characterizing proteins typically require physical or chemical
modification steps or cannot be used to examine individual molecules in solution. Ionic …

Protein plays a role as an indispensable macronutrient in human nutrition. The utilization of
new protein sources from plants requires a thorough investigation for application in foods …

Imaging samples in liquids with electron microscopy can provide unique insights into
biological systems, such as cells containing labelled proteins, and into processes of …

Here we describe a detailed protocol for both data collection and interpretation with respect
to ion mobility–mass spectrometry analysis of large protein assemblies. Ion mobility is a …

Proteomics is an increasingly powerful and indispensable technology in molecular cell
biology. It can be used to identify the components of small protein complexes and large …

Structural analysis of flexible macromolecular systems such as intrinsically disordered or
multidomain proteins with flexible linkers is a difficult task as high-resolution techniques are …

Cryoelectron microscopy of biological molecules is among the hottest growth areas in
biophysics and structural biology at present, and Frank is arguably the most distinguished …