Spermatogenesis is a complex differentiation process coordinated spatiotemporally across
and along seminiferous tubules. Cellular heterogeneity has made it challenging to obtain …

Human spermatogonia are target for exploration of adult stem cell characteristics and
potential source for the development of therapeutic applications. Almost 50 years ago, Yves …

Gene-expression programs define shared and species-specific phenotypes, but their
evolution remains largely uncharacterized beyond the transcriptome layer. Here we report …

Spermatogenesis is a highly regulated process that produces sperm to transmit genetic
information to the next generation. Although extensively studied in mice, our current …

The testis produces gametes through spermatogenesis and evolves rapidly at both the
morphological and molecular level in mammals,,,,–, probably owing to the evolutionary …

Sperm experience intense and varied selection that dramatically impacts the evolution of
sperm quality. Selection acts to ensure that sperm are fertilization-competent and able to …

The spermatozoon is a highly differentiated and polarized cell, with two main structures: the
head, containing a haploid nucleus and the acrosomal exocytotic granule, and the flagellum …

Germline and somatic genomes are in general the same in a multicellular organism.
However, programmed DNA elimination leads to a reduced somatic genome compared to …

Ageing and sexual selection are intimately linked. There is by now compelling evidence
from studies performed across diverse organisms that males allocating resources to mating …

Whole tissue RNASeq is the standard approach for studying gene expression divergence in
evolutionary biology and provides a snapshot of the comprehensive transcriptome for a …