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Exercise sustains the hallmarks of health
Y Qiu, B Fernández-García, HI Lehmann, G Li… - Journal of sport and …, 2023 - Elsevier
Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …
health. Regular moderate-intensity exercise improves all aspects of human health and is …
Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity
A Hammarstedt, S Gogg, S Hedjazifar… - Physiological …, 2018 - journals.physiology.org
The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …
However, it has a limited ability to expand by recruiting and/or differentiating available …
ER stress in obesity pathogenesis and management
A Ajoolabady, S Liu, DJ Klionsky, GYH Lip… - Trends in …, 2022 - cell.com
Given the unprecedented global pandemic of obesity, a better understanding of the etiology
of adiposity will be necessary to ensure effective management of obesity and related …
of adiposity will be necessary to ensure effective management of obesity and related …
ER stress and inflammation crosstalk in obesity
A Ajoolabady, C Lebeaupin, NN Wu… - Medicinal research …, 2023 - Wiley Online Library
The endoplasmic reticulum (ER) governs the proper folding of polypeptides and proteins
through various chaperones and enzymes residing within the ER organelle. Perturbation in …
through various chaperones and enzymes residing within the ER organelle. Perturbation in …
Inflammation‐mediated metabolic regulation in adipose tissue
S Xu, F Lu, J Gao, Y Yuan - Obesity Reviews, 2024 - Wiley Online Library
Chronic inflammation of adipose tissue is a prominent characteristic of many metabolic
diseases. Lipid metabolism in adipose tissue is consistently dysregulated during …
diseases. Lipid metabolism in adipose tissue is consistently dysregulated during …
The role of endoplasmic reticulum stress in cardiovascular disease and exercise
J Hong, K Kim, JH Kim, Y Park - International journal of …, 2017 - Wiley Online Library
Endoplasmic reticulum (ER) stress, which is highly associated with cardiovascular disease,
is triggered by a disturbance in ER function because of protein misfolding or an increase in …
is triggered by a disturbance in ER function because of protein misfolding or an increase in …
Endoplasmic reticulum unfolded protein response, aging and exercise: an update
The endoplasmic reticulum (ER) is a dynamic and multifunctional organelle responsible for
protein biosynthesis, folding, assembly and modifications. Loss of protein folding regulation …
protein biosynthesis, folding, assembly and modifications. Loss of protein folding regulation …
Exercise training promotes cardiac hydrogen sulfide biosynthesis and mitigates pyroptosis to prevent high-fat diet-induced diabetic cardiomyopathy
S Kar, HR Shahshahan, BT Hackfort, SK Yadav… - Antioxidants, 2019 - mdpi.com
Obesity increases the risk of develo** diabetes and subsequently, diabetic
cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H2S) and …
cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H2S) and …
Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte–endothelium interactions in PCOS
C Bañuls, S Rovira-Llopis, AM De Marañon, S Veses… - Metabolism, 2017 - Elsevier
Objective Polycystic ovary syndrome (PCOS) is associated with insulin resistance, which
can lead to metabolic syndrome (MetS). Oxidative stress and leukocyte–endothelium …
can lead to metabolic syndrome (MetS). Oxidative stress and leukocyte–endothelium …
[PDF][PDF] Immunometabolism-fit: How exercise and training can modify T cell and macrophage metabolism in health and disease.
Background: The term immunometabolism describes cellular and molecular metabolic
processes that control the immune system and the associated immune responses. Acute …
processes that control the immune system and the associated immune responses. Acute …