The lineage transition between epithelium and mesenchyme is a process known as
epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their …

Epithelial–mesenchymal transition (EMT) is a complex molecular program that regulates
changes in cell morphology and function during embryogenesis and tissue development …

Reactivation of an embryonic epithelial-to-mesenchymal (EMT) program is commonly
accepted as a core component of carcinoma progression. Collectively, EMT and …

A complex and highly orchestrated gene expression program chiefly establishes the
properties that define the adipocyte phenotype, in which the vast majority of factors are …

Bone-marrow-derived skeletal stem/stromal cell (SSC) self-renewal and function are critical
to skeletal development, homeostasis and repair. Nevertheless, the mechanisms controlling …

In this review, we explore the connections between epithelial‐mesenchymal transition (EMT)
and differentiation status. EMTs in development have been described as differentiation …

Reprogramming has been shown to involve EMT–MET; however, its role in cell
differentiation is unclear. We report here that in vitro differentiation of hESCs to hepatic …

Neural crest cells, which are specific to vertebrates, arise in the ectoderm but can generate
cell types that are typically categorized as mesodermal. This broad developmental potential …

Mechanical force modulates development, influences tissue homeostasis, and contributes to
disease. Forces sculpt tissue-level behaviors and direct cell fate by engaging …

Snail and Slug are zinc-finger transcription factors that play key roles in directing the
epithelial-mesenchymal transition (EMT) programs associated with normal development as …