Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …

INTRODUCTION We have identified previously unsuspected, directly pathogenic roles for
bacteriophage (phage) virions in bacterial infections. In particular, we report that …

Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …

Biofilms cause chronic infections in tissues or by develo** on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …

Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …