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Circadian and sleep dysfunction in Alzheimer's disease
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …
Circadian rhythm phase shifts caused by timed exercise vary with chronotype
BACKGROUND The circadian system entrains behavioral and physiological rhythms to
environmental cycles, and modern lifestyles disrupt this entrainment. We investigated a …
environmental cycles, and modern lifestyles disrupt this entrainment. We investigated a …
Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease
A promising new therapeutic target for the treatment of Alzheimer's disease (AD) is the
circadian system. Although patients with AD are known to have abnormal circadian rhythms …
circadian system. Although patients with AD are known to have abnormal circadian rhythms …
Circadian rhythm and Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder with a growing epidemiological
importance characterized by significant disease burden. Sleep-related pathological …
importance characterized by significant disease burden. Sleep-related pathological …
Environmental pollution and extreme weather conditions: insights into the effect on mental health
Environmental pollution exposures, including air, soil, water, light, and noise pollution, are
critical issues that may implicate adverse mental health outcomes. Extreme weather …
critical issues that may implicate adverse mental health outcomes. Extreme weather …
Effects of light treatment on sleep, cognition, mood, and behavior in Alzheimer's disease: a systematic review
Background: Bright light treatment is a therapeutic intervention mainly used to treat sleep
and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of …
and circadian disturbances in Alzheimer's disease (AD) patients. Recently, a handful of …
New insights into non-transcriptional regulation of mammalian core clock proteins
Mammalian circadian rhythms drive∼ 24 h periodicity in a wide range of cellular processes,
temporally coordinating physiology and behaviour within an organism, and synchronising …
temporally coordinating physiology and behaviour within an organism, and synchronising …
Non-invasive 40-Hz light flicker ameliorates Alzheimer's-associated rhythm disorder via regulating central circadian clock in mice
Y Yao, Y Ying, Q Deng, W Zhang, H Zhu, Z Lin… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) patients often exhibit perturbed circadian rhythm with fragmented
sleep before disease onset. This study was designed to evaluate the effect of a 40-Hz light …
sleep before disease onset. This study was designed to evaluate the effect of a 40-Hz light …
Positive effect of timed blue-enriched white light on sleep and cognition in patients with mild and moderate Alzheimer's disease
SJ Kim, SH Lee, IB Suh, JW Jang, JH Jhoo, JH Lee - Scientific reports, 2021 - nature.com
Conflicting results have been reported regarding the effectiveness of light treatment (LT) in
patients with Alzheimer's disease (AD). We investigated the effectiveness of blue-enriched …
patients with Alzheimer's disease (AD). We investigated the effectiveness of blue-enriched …