[HTML][HTML] Strategies to prolong the residence time of drug delivery systems on ocular surface

B Grassiri, Y Zambito, A Bernkop-Schnürch - Advances in colloid and …, 2021 - Elsevier
Ocular diseases may be treated via different routes of administration, such as topical,
intracameral, intravitreal, oral and parenteral. Among them the topical route is most accepted …

Thiolated polymers: Bioinspired polymers utilizing one of the most important bridging structures in nature

C Leichner, M Jelkmann… - Advanced Drug Delivery …, 2019 - Elsevier
Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …

Development of Thiol-Maleimide hydrogels incorporating graphene-based nanomaterials for cancer chemo-photothermal therapy

FJP Costa, M Nave, R Lima-Sousa, CG Alves… - International Journal of …, 2023 - Elsevier
Nano-sized materials have been widely explored in the biomedicine field, especially due to
their ability to encapsulate drugs intended to be delivered to cancer cells. However …

Thiolated Poly‐and Oligosaccharide‐Based Hydrogels for Tissue Engineering and Wound Healing

S Noreen, A Bernkop‐Schnürch - Advanced Functional …, 2024 - Wiley Online Library
Due to thiolation of poly‐and oligosaccharides numerous favorable properties for tissue
engineering and wound healing can be introduced. Poly‐and oligosaccharides can be …

Mucoadhesive hydrogels for buccal drug delivery: In vitro-in vivo correlation study

RA Baus, F Zahir-Jouzdani, S Dünnhaupt… - European Journal of …, 2019 - Elsevier
Aim It was the aim of this study to assess in vitro methods for the characterization of
mucoadhesive hydrogels for their potential to predict the residence time on human buccal …

Thiolated hyaluronic acid as versatile Mucoadhesive polymer: from the chemistry behind to product developments—what are the capabilities?

J Griesser, G Hetényi, A Bernkop-Schnürch - Polymers, 2018 - mdpi.com
Within the last decade, intensive research work has been conducted on thiolated hyaluronic
acids (HA-SH). By attaching sulfhydryl ligands onto naturally occurring hyaluronic acid …

Hyaluronan and its derivatives for ophthalmology: Recent advances and future perspectives

GH Ángeles, K Nešporová - Carbohydrate Polymers, 2021 - Elsevier
Ophthalmic disorders are amid the most common pathologies worldwide. In this regard,
hyaluronan (HA) has gained widespread use in eye surgeries and treatment of eye …

Thiolated-polymer-based nanoparticles as an avant-garde approach for anticancer therapies—reviewing thiomers from chitosan and hyaluronic acid

R Grosso, MV de-Paz - Pharmaceutics, 2021 - mdpi.com
Thiomers (or thiolated polymers) have broken through as avant-garde approaches in
anticancer therapy. Their distinguished reactivity and properties, closely linked to their final …

[HTML][HTML] Thiolated cyclodextrins: New perspectives for old excipients

MH Asim, M Ijaz, AC Rösch… - Coordination Chemistry …, 2020 - Elsevier
Thiolated cyclodextrins (CDs) are obtained by covalent attachment of thiol moieties on the
oligomeric backbone of different types of CDs. First, thiolated CDs were introduced in the …

Lyophilized progenitor tenocyte extracts: Sterilizable cytotherapeutic derivatives with antioxidant properties and hyaluronan hydrogel functionalization effects

A Laurent, A Porcello, A Jeannerat, C Peneveyre… - Antioxidants, 2023 - mdpi.com
Cultured primary progenitor tenocytes in lyophilized form were previously shown to possess
intrinsic antioxidant properties and hyaluronan-based hydrogel viscosity-modulating effects …