[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application

ME Ladd, P Bachert, M Meyerspeer, E Moser… - Progress in nuclear …, 2018‏ - Elsevier
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

Ranolazine: a potential anti-metastatic drug targeting voltage-gated sodium channels

MBA Djamgoz - British Journal of Cancer, 2024‏ - nature.com
Background Multi-faceted evidence from a range of cancers suggests strongly that de novo
expression of voltage-gated sodium channels (VGSCs) plays a significant role in driving …

Biomedical applications of sodium MRI in vivo

G Madelin, RR Regatte - Journal of Magnetic Resonance …, 2013‏ - Wiley Online Library
In this article we present an up‐to‐date overview of the potential biomedical applications of
sodium magnetic resonance imaging (MRI) in vivo. Sodium MRI is a subject of increasing …

Sodium MRI: methods and applications

G Madelin, JS Lee, RR Regatte, A Jerschow - Progress in nuclear magnetic …, 2014‏ - Elsevier
Sodium NMR spectroscopy and MRI have become popular in recent years through the
increased availability of high-field MRI scanners, advanced scanner hardware and improved …

Diffusion-weighted imaging with apparent diffusion coefficient map** for breast cancer detection as a stand-alone parameter: comparison with dynamic contrast …

K Pinker, L Moy, EJ Sutton, RM Mann… - Investigative …, 2018‏ - journals.lww.com
Purpose The aims of this study were to compare dynamic contrast-enhanced (DCE)
magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) with apparent …

Background, current role, and potential applications of radiogenomics

K Pinker, F Shitano, E Sala, RK Do… - Journal of Magnetic …, 2018‏ - Wiley Online Library
With the genomic revolution in the early 1990s, medical research has been driven to study
the basis of human disease on a genomic level and to devise precise cancer therapies …

Sodium homeostasis in the tumour microenvironment

TK Leslie, AD James, F Zaccagna, JT Grist… - … et Biophysica Acta (BBA …, 2019‏ - Elsevier
The concentration of sodium ions (Na+) is raised in solid tumours and can be measured at
the cellular, tissue and patient levels. At the cellular level, the Na+ gradient across the …

The potential of multiparametric MRI of the breast

K Pinker, TH Helbich, EA Morris - The British journal of …, 2017‏ - academic.oup.com
MRI is an essential tool in breast imaging, with multiple established indications. Dynamic
contrast-enhanced MRI (DCE-MRI) is the backbone of any breast MRI protocol and has an …

[HTML][HTML] In vivo evidence for voltage-gated sodium channel expression in carcinomas and potentiation of metastasis

MBA Djamgoz, SP Fraser, WJ Brackenbury - Cancers, 2019‏ - mdpi.com
A wide body of evidence suggests that voltage-gated sodium channels (VGSCs) are
expressed de novo in several human carcinomas where channel activity promotes a variety …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021‏ - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …