Revisiting fibrosis in inflammatory bowel disease: the gut thickens

S D'Alessio, F Ungaro, D Noviello, S Lovisa… - Nature Reviews …, 2022 - nature.com
Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

Evidence-based clinical practice guidelines for inflammatory bowel disease

K Matsuoka, T Kobayashi, F Ueno, T Matsui… - Journal of …, 2018 - Springer
Inflammatory bowel disease (IBD) is a chronic disorder involving mainly the intestinal tract,
but possibly other gastrointestinal and extraintestinal organs. Although etiology is still …

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind …

J Panés, D García-Olmo, G Van Assche, JF Colombel… - The Lancet, 2016 - thelancet.com
Background Complex perianal fistulas in Crohn's disease are challenging to treat.
Allogeneic, expanded, adipose-derived stem cells (Cx601) are a promising new therapeutic …

Inflammatory bowel disease in pregnancy clinical care pathway: a report from the American Gastroenterological Association IBD Parenthood Project Working Group

U Mahadevan, C Robinson, N Bernasko… - Inflammatory bowel …, 2019 - academic.oup.com
In the United States, approximately 0.5% of the population, or 1.6 million people, have
inflammatory bowel disease (IBD)—Crohn's disease (CD) and ulcerative colitis (UC). 1, 2 Of …

The Toronto consensus statements for the management of inflammatory bowel disease in pregnancy

GC Nguyen, CH Seow, C Maxwell, V Huang, Y Leung… - Gastroenterology, 2016 - Elsevier
Background & Aims The management of inflammatory bowel disease (IBD) poses a
particular challenge during pregnancy because the health of both the mother and the fetus …

[HTML][HTML] The diagnostic approach to monogenic very early onset inflammatory bowel disease

HH Uhlig, T Schwerd, S Koletzko, N Shah… - Gastroenterology, 2014 - Elsevier
Patients with a diverse spectrum of rare genetic disorders can present with inflammatory
bowel disease (monogenic IBD). Patients with these disorders often develop symptoms …

Crohn's disease management after intestinal resection: a randomised trial

P De Cruz, MA Kamm, AL Hamilton, KJ Ritchie… - The Lancet, 2015 - thelancet.com
Summary Background Most patients with Crohn's disease need an intestinal resection, but a
majority will subsequently experience disease recurrence and require further surgery. This …

Crohn's disease

J Torres, S Mehandru, JF Colombel, L Peyrin-Biroulet - The Lancet, 2017 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with
increasing incidence worldwide. Crohn's disease might result from a complex interplay …

Mucosal healing in inflammatory bowel diseases: a systematic review

MF Neurath, SPL Travis - Gut, 2012 - gut.bmj.com
Recent studies have identified mucosal healing on endoscopy as a key prognostic
parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the …

Biologic agents for IBD: practical insights

S Danese, L Vuitton, L Peyrin-Biroulet - … reviews Gastroenterology & …, 2015 - nature.com
Six biologic agents are currently approved for the treatment of IBD: four anti-TNF agents
(infliximab, adalimumab, golimumab and certolizumab pegol) and two anti-integrin agents …