Dapagliflozin alleviates arsenic trioxide-induced hepatic injury in rats via modulating PI3K/AkT/mTOR, STAT3/SOCS3/p53/MDM2 signaling pathways and miRNA-21 …

BA Abdel-Wahab, EAM El-Shoura, MS Habeeb… - International …, 2024‏ - Elsevier
Dapagliflozin (DPG) is a sodium-glucose co-transporter 2 inhibitor that is commonly used in
the treatment of type 2 diabetes. However, studies have shown that DPG has a protective …

Lactoferrin alleviates gentamicin-induced acute kidney injury in rats by suppressing ferroptosis: Highlight on ACSL4, SLC7A11, NCOA4, FSP1 pathways and miR …

RM Salama, SF Darwish, R Yehia, AA Sallam… - Food and Chemical …, 2024‏ - Elsevier
The use of gentamicin (GNT) is associated with acute kidney injury (AKI). Ferroptosis is a
newly recognized iron-dependent, non-apoptotic cell death that can lead to AKI. Lactoferrin …

[HTML][HTML] Repurposing Dapagliflozin for Mitigation of the Kidney Injury Triggered by Cadmium in Rats: Role of Autophagy, Apoptosis, and the SIRT1/Nrf2/HO-1 Pathway

HH Arab, MM Althobaiti, AS Alharthi, EO Almalki… - Pharmaceuticals, 2024‏ - mdpi.com
Background/Objectives: The antioxidant/antiapoptotic features of dapagliflozin (DPG) have
mediated its beneficial actions against several experimental models. However, no studies …

Carvacrol amended Vancomycin-induced nephrotoxicity in rats via regulating Nrf2/HO-1, IKBβ/NF-κB and Bax/Bacl2 pathways

AA Elhemiely, R Yahia, HA Abd El Aal - Azhar International Journal …, 2025‏ - journals.ekb.eg
Drug-induced kidney injury is considered as a dangerous condition caused morbidity and
mortality and most notably Vancomycin induced nephrotoxicity via oxidative stress …

[معلومات الإصدار][C] 七氟烷对大鼠肾缺血再灌注损伤的影响及其机制

杨传铭, 易铭, **冰, 张一粟, **晓红 - 中华解剖与临床杂志, 2023