Epigenetic mechanisms of inflammasome regulation
G Poli, C Fabi, MM Bellet, C Costantini… - International journal of …, 2020 - mdpi.com
The innate immune system represents the host's first-line defense against pathogens, dead
cells or environmental factors. One of the most important inflammatory pathways is …
cells or environmental factors. One of the most important inflammatory pathways is …
Identification of circRNA-lncRNA-miRNA-mRNA competitive endogenous RNA network as novel prognostic markers for acute myeloid leukemia
Y Cheng, Y Su, S Wang, Y Liu, L **, Q Wan, Y Liu, C Li… - Genes, 2020 - mdpi.com
Background: Acute myeloid leukemia (AML) is one of the most common malignant and
aggressive hematologic tumors, and its pathogenesis is associated with abnormal post …
aggressive hematologic tumors, and its pathogenesis is associated with abnormal post …
AIM2 and psoriasis
Y Zhang, X Xu, H Cheng, F Zhou - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease occurring worldwide, with multiple systemic
complications, which seriously affect the quality of life and physical and mental health of …
complications, which seriously affect the quality of life and physical and mental health of …
miR-23a, miR-146a and miR-301a confer predisposition to Vogt-Koyanagi-Harada syndrome but not to Behcet's disease
S Hou, Z Ye, D Liao, L Bai, Y Liu, J Zhang, A Kijlstra… - Scientific reports, 2016 - nature.com
Ninety-eight miRNAs are involved in the immune response. However, the genetic roles of
these miRNAs remain unclear in Behcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) …
these miRNAs remain unclear in Behcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) …
Inflammasomes are neuroprotective targets for sex steroids
A Slowik, C Beyer - The Journal of steroid biochemistry and molecular …, 2015 - Elsevier
Neuroinflammation in the central nervous system is triggered by toxic stimuli or degenerative
events, orchestrates the interplay of brain-intrinsic immune cells and neighboring neural …
events, orchestrates the interplay of brain-intrinsic immune cells and neighboring neural …
miR-143 suppresses the proliferation of NSCLC cells by inhibiting the epidermal growth factor receptor
HB Zhang, LC Sun, L Ling… - Experimental and …, 2016 - spandidos-publications.com
MicroRNAs (miRs) regulate the proliferation and metastasis of numerous cancer cell types. It
was previously reported that miR-143 levels were downregulated in non-small cell lung …
was previously reported that miR-143 levels were downregulated in non-small cell lung …
[HTML][HTML] New Insights into Nucleic Acid Sensor AIM2: The Potential Benefit in Targeted Therapy for Cancer
The AIM2 inflammasome represents a multifaceted oligomeric protein complex within the
innate immune system, with the capacity to perceive double-stranded DNA (dsDNA) and …
innate immune system, with the capacity to perceive double-stranded DNA (dsDNA) and …
Interaction among inflammasome, autophagy and non-coding RNAs: new horizons for drug
Q Pu, P Lin, Z Wang, P Gao, S Qin… - Precision clinical …, 2019 - academic.oup.com
Autophagy and inflammasomes are shown to interact in various situations including
infectious disease, cancer, diabetes and neurodegeneration. Since multiple layers of …
infectious disease, cancer, diabetes and neurodegeneration. Since multiple layers of …
[HTML][HTML] Down-regulation of HSP40 gene family following OCT4B1 suppression in human tumor cell lines
Objective (s): The OCT4B1, as one of OCT4 variants, is expressed in cancer cell lines and
tissues more than other variants and plays an important role in apoptosis and stress (heat …
tissues more than other variants and plays an important role in apoptosis and stress (heat …
Cellular microRNAs and picornaviral infections
microRNAs (miRNAs) are a subtype of short, endogenous, and non-coding RNAs, which
post-transcriptionally regulate gene expression. The miRNA-mediated gene silencing …
post-transcriptionally regulate gene expression. The miRNA-mediated gene silencing …